H
Hong Ji
Researcher at California National Primate Research Center
Publications - 48
Citations - 5526
Hong Ji is an academic researcher from California National Primate Research Center. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 18, co-authored 40 publications receiving 5097 citations. Previous affiliations of Hong Ji include University of Cincinnati Academic Health Center & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Epigenetic memory in induced pluripotent stem cells
Kibem Kim,Akiko Doi,Bo Wen,K. Ng,Rui Zhao,Patrick Cahan,Jonghwan Kim,Martin J. Aryee,Hong Ji,Lauren I.R. Ehrlich,Lauren I.R. Ehrlich,A. Yabuuchi,A. Takeuchi,K. C. Cunniff,H. Hongguang,Shannon McKinney-Freeman,Olaia Naveiras,T. J. Yoon,T. J. Yoon,Rafael A. Irizarry,Namyoung Jung,Jun Seita,Jacob H. Hanna,Peter Murakami,Rudolf Jaenisch,Ralph Weissleder,Stuart H. Orkin,Irving L. Weissman,Andrew P. Feinberg,George Q. Daley +29 more
TL;DR: It is observed that low-passage induced pluripotent stem cells (iPSCs) derived by factor-based reprogramming of adult murine tissues harbour residual DNA methylation signatures characteristic of their somatic tissue of origin, which favours their differentiation along lineages related to the donor cell, while restricting alternative cell fates.
Epigenetic memory in induced pluripotent stem cells
Kibem Kim,Akiko Doi,Bo Wen,K. Ng,Rui Zhao,Patrick Cahan,Jonghwan Kim,Martin J. Aryee,Hong Ji,Lauren I.R. Ehrlich,Lauren I.R. Ehrlich,A. Yabuuchi,A. Takeuchi,K. C. Cunniff,H. Hongguang,Shannon McKinney-Freeman,Olaia Naveiras,T. J. Yoon,T. J. Yoon,Rafael A. Irizarry,Namyoung Jung,Jun Seita,Jacob H. Hanna,Peter Murakami,Rudolf Jaenisch,Ralph Weissleder,Stuart H. Orkin,Irving L. Weissman,Andrew P. Feinberg,George Q. Daley +29 more
TL;DR: The authors showed that low-passage induced pluripotent stem cells (iPSCs) derived by factor-based reprogramming of adult murine tissues harbor residual DNA methylation signatures characteristic of their somatic tissue of origin.
Journal ArticleDOI
Comprehensive methylome map of lineage commitment from haematopoietic progenitors.
Hong Ji,Lauren I.R. Ehrlich,Jun Seita,Peter Murakami,Akiko Doi,Paul Lindau,Hwajin Lee,Martin J. Aryee,Rafael A. Irizarry,Kitai Kim,Derrick J. Rossi,Derrick J. Rossi,Matthew A. Inlay,Thomas Serwold,Thomas Serwold,Holger Karsunky,Lena Ho,George Q. Daley,Irving L. Weissman,Andrew P. Feinberg +19 more
TL;DR: The results directly demonstrate that modulation of DNA methylation occurs during lineage-specific differentiation and defines a comprehensive map of the methylation and transcriptional changes that accompany myeloid versus lymphoid fate decisions.
Journal ArticleDOI
Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution
Hari K. Somineni,Xue Zhang,Jocelyn M. Biagini Myers,Melinda Butsch Kovacic,Melinda Butsch Kovacic,Ashley Ulm,Noelle R. Jurcak,Patrick H. Ryan,Patrick H. Ryan,Gurjit K. Khurana Hershey,Hong Ji +10 more
TL;DR: The findings suggest a possible role of TET1 methylation in asthmatic patients and response to TRAP.
Journal ArticleDOI
Genetic and epigenetic influence on the response to environmental particulate matter
TL;DR: Recent findings on the genetic and epigenetic regulation of responses to ambient air pollutants, specifically respirable PM, and their association with the development of allergic disorders are summarized.