H
Houman Savoji
Researcher at University of Toronto
Publications - 35
Citations - 689
Houman Savoji is an academic researcher from University of Toronto. The author has contributed to research in topics: Tissue engineering & Membrane. The author has an hindex of 12, co-authored 26 publications receiving 380 citations. Previous affiliations of Houman Savoji include University Health Network & Sharif University of Technology.
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Journal ArticleDOI
Cardiovascular disease models: A game changing paradigm in drug discovery and screening
Houman Savoji,Houman Savoji,Mohammad Hossein Mohammadi,Mohammad Hossein Mohammadi,Naimeh Rafatian,Masood Khaksar Toroghi,Erika Yan Wang,Yimu Zhao,Anastasia Korolj,Samad Ahadian,Milica Radisic,Milica Radisic +11 more
TL;DR: Current in vitro, in vivo, and in silico platforms for modelling healthy and pathological cardiac tissues and their advantages and disadvantages for drug screening and discovery applications are described and a roadmap for employing these non-animal platforms in assessing drug cardiotoxicity and safety is suggested.
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Skin Tissue Substitutes and Biomaterial Risk Assessment and Testing.
TL;DR: This review summarizes the past and present advances in in vitro, in vivo and clinical applications of tissue-engineered skins, and discusses the role of immunomodulatory biomaterials and biomMaterials risk assessment in skin tissue engineering.
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Electrospun Nanofiber Scaffolds and Plasma Polymerization: A Promising Combination Towards Complete, Stable Endothelial Lining for Vascular Grafts
Houman Savoji,Houman Savoji,Afra Hadjizadeh,Marion Maire,Abdellah Ajji,Michael R. Wertheimer,Sophie Lerouge,Sophie Lerouge +7 more
TL;DR: Electrospun poly(ethylene terephthalate) mats are combined with an amine-rich thin plasma-polymerized coating, designated "L-PPE:N", which significantly improves the adhesion and growth of human umbilical vein endothelial cells (HUVEC) and their resistance to flow-induced shear stress.
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Towards chamber specific heart-on-a-chip for drug testing applications.
Yimu Zhao,Naimeh Rafatian,Erika Yan Wang,Qinghua Wu,Benjamin F.L. Lai,Rick Xing Ze Lu,Houman Savoji,Milica Radisic +7 more
TL;DR: Current heart-on-a-chip approaches incorporate biological, electrical, mechanical, and topographical cues to facilitate tissue maturation, therefore improving the predictive power for the chamber-specific therapeutic effects targeting adult human.
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Facile Method for Fabrication of Meter-Long Multifunctional Hydrogel Fibers with Controllable Biophysical and Biochemical Features.
Bahram Mirani,Erik Pagan,Shahla Shojaei,Seyed Mohammad Hossein Dabiri,Houman Savoji,Houman Savoji,Mehdi Mehrali,Mahshid Sam,Jehad Alsaif,Rustom B. Bhiladvala,Alireza Dolatshahi-Pirouz,Milica Radisic,Milica Radisic,Mohsen Akbari +13 more
TL;DR: A novel biofabrication method for fabrication of grooved solid and hollow hydrogel fibers with control over their cross-sectional shape, surface morphology, porosity, and material composition was described.