H
Howard Lippton
Researcher at Tulane University
Publications - 105
Citations - 4494
Howard Lippton is an academic researcher from Tulane University. The author has contributed to research in topics: Vasodilation & Vascular resistance. The author has an hindex of 30, co-authored 105 publications receiving 4466 citations. Previous affiliations of Howard Lippton include Louisiana State University & University Medical Center New Orleans.
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Journal Article
Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.
Louis J. Ignarro,Howard Lippton,J C Edwards,William H. Baricos,Albert L. Hyman,P. J. Kadowitz,Carl A. Gruetter +6 more
PatentDOI
Diuretic and antinatriuretic responses produced by the endogenous opioid-like peptide, nociceptin (orphanin FQ)
TL;DR: The results indicate that in conscious rats, nociceptin produces a selective water diuresis via a central nervous system mechanism independent of kappa-opioid receptors, and suggest that endogenous nocICEptin may be a novel peptide involved in the central control of water balance and ultimately in the regulation of arterial blood pressure.
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Effects of endothelin in the systemic and renal vascular beds in vivo
TL;DR: Although endothelin was initially reported as an endothelial-derived peptide with vasoconstrictor properties, the present data suggest that the physiologic effect of this peptide may be vasodilation.
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Endothelin produces pulmonary vasoconstriction and systemic vasodilation.
TL;DR: The potent vasodilator activity of endothelin in the systemic vascular bed and its weak effect on pulmonary vessels suggest thatendothelin may be more important in the regulation of peripheral vasomotor tone than the pulmonary vascular bed.
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Adrenomedullin dilates the pulmonary vascular bed in vivo.
TL;DR: The present data suggest that ADM-(13-52) or a similar ADM fragment is responsible for the marked pulmonary vasodilator activity of ADM-1-52 in vivo.