H
Hsin-Hung Chen
Researcher at National Chung Hsing University
Publications - 17
Citations - 738
Hsin-Hung Chen is an academic researcher from National Chung Hsing University. The author has contributed to research in topics: Photothermal therapy & Cancer. The author has an hindex of 10, co-authored 15 publications receiving 517 citations. Previous affiliations of Hsin-Hung Chen include National Tsing Hua University.
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Journal ArticleDOI
Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma.
Yuan-Chung Tsai,Priya Vijayaraghavan,Wen-Hsuan Chiang,Hsin-Hung Chen,Hsin-Hung Chen,Te-I Liu,Ming-Yin Shen,Ming-Yin Shen,Ayumu Omoto,Masao Kamimura,Kohei Soga,Hsin-Cheng Chiu +11 more
TL;DR: In vitro and in vivo data strongly indicate that the ANG-IMNPs were capable of selectively delivering dual photosensitizers to brain astrocytoma tumors for effective PDT/PTT in conjugation with a substantially improved median survival.
Journal ArticleDOI
Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy.
Chia-Chian Hung,Wen-Chia Huang,Yi-Wen Lin,Ting-Wei Yu,Hsin-Hung Chen,Sung-Chyr Lin,Wen-Hsuan Chiang,Hsin-Cheng Chiu +7 more
TL;DR: The prominent imaging-guided photothermal therapy of ICG/DOX-loaded nanoparticles after tumor accumulation induced extensive tumor tissue/vessel ablation, which further promoted their extravasation and DOX tumor permeation, thus effectively suppressing tumor growth.
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Hierarchically targetable polysaccharide-coated solid lipid nanoparticles as an oral chemo/thermotherapy delivery system for local treatment of colon cancer.
Ming-Yin Shen,Te-I Liu,Ting-Wei Yu,Reesha Kv,Wen-Hsuan Chiang,Yuan-Chung Tsai,Hsin-Hung Chen,Sung-Chyr Lin,Hsin-Cheng Chiu +8 more
TL;DR: The evaluation of the in vivo antitumor efficacy of the hierarchically targetable SLN therapy system by oral administration showed the effective inhibition of primary colon tumors and peritoneal metastasis in terms of the ascites volume and tumor nodule number and size, along with the absence of systemic side effects.
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Superparamagnetic hollow hybrid nanogels as a potential guidable vehicle system of stimuli-mediated MR imaging and multiple cancer therapeutics.
Wen-Hsuan Chiang,Viet Thang Ho,Hsin-Hung Chen,Wen-Chia Huang,Yi-Fong Huang,Sung-Chyr Lin,Chorng-Shyan Chern,Hsin-Cheng Chiu +7 more
TL;DR: This work demonstrates that the hollow inorganic/organic hybrid nanogels hold great potential to serve as a multimodal theranostic vehicle functionalized with such desirable features as the guidable delivery of stimuli-mediated diagnostic imaging and hyperthermia/chemotherapies.
Journal ArticleDOI
Monocytic delivery of therapeutic oxygen bubbles for dual-modality treatment of tumor hypoxia.
Wen-Chia Huang,Ming-Yin Shen,Hsin-Hung Chen,Sung-Chyr Lin,Wen-Hsuan Chiang,Pei-Hsuan Wu,Chien-Wen Chang,Chi-Shiun Chiang,Hsin-Cheng Chiu +8 more
TL;DR: This work demonstrates that this oxygen/therapeutic co-delivery via tumortropic monocytes toward tumor hypoxia is promising for improving PDT efficacy.