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Ming-Yin Shen

Researcher at National Tsing Hua University

Publications -  12
Citations -  515

Ming-Yin Shen is an academic researcher from National Tsing Hua University. The author has contributed to research in topics: Nanogel & Photothermal therapy. The author has an hindex of 7, co-authored 11 publications receiving 382 citations. Previous affiliations of Ming-Yin Shen include National Taiwan University & China Medical University (Taiwan).

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Journal ArticleDOI

Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma.

TL;DR: In vitro and in vivo data strongly indicate that the ANG-IMNPs were capable of selectively delivering dual photosensitizers to brain astrocytoma tumors for effective PDT/PTT in conjugation with a substantially improved median survival.
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Functionalized polymersomes with outlayered polyelectrolyte gels for potential tumor-targeted delivery of multimodal therapies and MR imaging.

TL;DR: The high magnetic relaxivity of the tumor-targeting NCPs coupled with their enhanced cellular uptake considerably promoted the MRI contrast of targeted cancer cells, demonstrating the great potential of the FA-decorated SPION/DOX-loaded N CPs as an advanced cancer theranostic nanodevice.
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Hierarchically targetable polysaccharide-coated solid lipid nanoparticles as an oral chemo/thermotherapy delivery system for local treatment of colon cancer.

TL;DR: The evaluation of the in vivo antitumor efficacy of the hierarchically targetable SLN therapy system by oral administration showed the effective inhibition of primary colon tumors and peritoneal metastasis in terms of the ascites volume and tumor nodule number and size, along with the absence of systemic side effects.
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Monocytic delivery of therapeutic oxygen bubbles for dual-modality treatment of tumor hypoxia.

TL;DR: This work demonstrates that this oxygen/therapeutic co-delivery via tumortropic monocytes toward tumor hypoxia is promising for improving PDT efficacy.
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pH-Responsive therapeutic solid lipid nanoparticles for reducing P-glycoprotein-mediated drug efflux of multidrug resistant cancer cells.

TL;DR: The C-PEG-SLN is a promising platform for the delivery of therapeutic agents for MDR cancer chemotherapy via enhanced permeability and retention effect, the enhanced passive tumor accumulation due to the loose intercellular junctions of endothelial cells lining inside blood vessels at tumor site, and the lack of lymphatic drainage.