H
Hua Lin Wu
Researcher at National Cheng Kung University
Publications - 193
Citations - 5624
Hua Lin Wu is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Thrombomodulin & Angiogenesis. The author has an hindex of 41, co-authored 186 publications receiving 5167 citations. Previous affiliations of Hua Lin Wu include National Taiwan University.
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Journal ArticleDOI
Detection of HCV RNA in saliva, urine, seminal fluid, and ascites
TL;DR: The presence ofHCV RNA in saliva and seminal fluid of patients positive for serum HCV RNA suggests sexual and household contact as likely modes of nonparenteral transmission of type C hepatitis.
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Suppression of angiogenesis and tumor growth by the inhibitor K1–5 generated by plasmin-mediated proteolysis
Renhai Cao,Hua Lin Wu,Niina Veitonmäki,Philip A. Linden,Jacob Farnebo,Guey Yueh Shi,Yihai Cao +6 more
TL;DR: It is demonstrated that urokinase-activated plAsmin can process plasminogen to release an angiogenesis inhibitor, K1-5 (protease- activated kringles 1-5), and this findings suggest that the plasmine-mediated proteolysis may be involved in the negative switch ofAngiogenesis.
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Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response.
Chung-Sheng Shi,Guey Yueh Shi,Hsi-Min Hsiao,Yuan-Chung Kao(高遠忠),Kuan-Lin Kuo,Chih-Yuan Ma,Cheng Hsiang Kuo,Bi-Ing Chang,Chuan Fa Chang,Chun-Hung Lin,Chi-Huey Wong,Hua Lin Wu +11 more
TL;DR: It is demonstrated that recombinant N-terminal lectinlike domain of TM (rTMD1) functions as a protective agent against sepsis caused by Gram-negative bacterial infections and can be used to defend against bacterial infection and inhibit LPS-induced inflammatory responses, suggesting that rT MD1 may be valuable in the treatment of severe inflammation in sepsi.
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Thrombomodulin-mediated cell adhesion: involvement of its lectin-like domain.
Huey-Chun Huang,Guey Yueh Shi,Shinn Jong Jiang,Chung-Sheng Shi,Chun-Mei Wu,Hsi-Yuan Yang,Hua Lin Wu +6 more
TL;DR: Thrombomodulin can function as a Ca2+-dependent cell-to-cell adhesion molecule and binding of specific carbohydrates to the lectin-like domain is essential for this specific function.
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Intramyocardial Peptide Nanofiber Injection Improves Postinfarction Ventricular Remodeling and Efficacy of Bone Marrow Cell Therapy in Pigs
Yi-Dong Lin,Ming Long Yeh,Yu Jen Yang,Da Ching Tsai,Ting Yu Chu,Ya Yun Shih,Min Yao Chang,Yen Wen Liu,Alan C.L. Tang,Tsai Yun Chen,Chwan Yau Luo,Kung Chao Chang,Jyh Hong Chen,Hua Lin Wu,Tin Kan Hung,Patrick C.H. Hsieh,Patrick C.H. Hsieh +16 more
TL;DR: It is demonstrated that NF injection alone prevents ventricular remodeling, whereas cell implantation with NFs improves cell retention and cardiac functions after MI in pigs.