Hua Wei

TL;DR: Results showed that the nanosized magnetic nanoparticles exhibited an enrichment factor (cancer cells over normal cells) of 1:10,000,000 in a magnetic field through the binding of IO-Ab on the cell surface that resulted in the preferential capture of the cancer cells.

TL;DR: The results indicated that 5 mg/L AgNPs inhibited ~50% of the growth of 106 colony forming units per milliliter (cfu/mL) E. coli cells in liquid Luria–Bertani (LB) medium, and dose-dependent antimicrobial activity was higher at increased temperature (37°C) but was lower when the AgNPS were treated with acid at pH 2 before exposure to the bacteria.

TL;DR: The antibacterial mechanism of ε-PL against E. coli O157:H7 may be attributed to disturbance on membrane integrity, oxidative stress by ROS, and effects on various gene expressions, such as regulation of oxidative stress, SOS response, and changes in virulence.

TL;DR: RT-qPCR data revealed that AgNPs induced greater changes in gene expression with relevance to oxidative stress, apoptosis, and ion transport, which proved that the NPs chemical composition played a critical role in their in vivo biodistribution and toxicity.

TL;DR: Smaller IOMNs more effectively changed the expression level of sensitive genes related to oxidant stress, iron transport, metabolic process, apoptosis, and others, as well as the level of iron in the heart decreased in all IOMN exposed groups.