H
Huahua Yue
Researcher at South China Normal University
Publications - 12
Citations - 733
Huahua Yue is an academic researcher from South China Normal University. The author has contributed to research in topics: Chemistry & Nucleic acid. The author has an hindex of 6, co-authored 9 publications receiving 197 citations.
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Journal ArticleDOI
Simultaneous dual-gene diagnosis of SARS-CoV-2 based on CRISPR/Cas9-mediated lateral flow assay.
Erhu Xiong,Erhu Xiong,Ling Jiang,Tian Tian,Menglu Hu,Huahua Yue,Mengqi Huang,Wei Lin,Yongzhong Jiang,Debin Zhu,Xiaoming Zhou +10 more
TL;DR: A CRISPR/Cas9-mediated triple-line lateral flow assay (TL-LFA) combined with multiplex reverse transcription-recombinase polymerase amplification (RT-RPA) for rapid and simultaneous dual-gene detection of SARS-CoV-2 in a single strip test is developed.
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Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction.
TL;DR: APC-Cas can identify low numbers of S .
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Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing
TL;DR: The results demonstrate that the GO-mediated Cas9/sgRNA delivery system has potential as a new approach for biomedical research and targeted gene engineering applications and can protect sgRNA from enzymatic degradation, thus exhibiting extremely high stability, which is critical for future in vivo applications.
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Droplet Cas12a Assay Enables DNA Quantification from Unamplified Samples at the Single-Molecule Level.
Huahua Yue,Bowen Shu,Bowen Shu,Tian Tian,Erhu Xiong,Mengqi Huang,Debin Zhu,Jian Sun,Qing Liu,Shichan Wang,Yirong Li,Xiaoming Zhou +11 more
TL;DR: In this paper, a CRISPR-Cas12a-based molecular diagnostic technique for amplification-free and absolute quantification of DNA at the single-molecule level is presented.
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Advances in Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Diagnostic Assays Assisted by Micro/Nanotechnologies.
TL;DR: A detailed summary of which micro/nanotechnologies play roles in the advancement of CRISPR diagnosis and how they are involved can be found in this paper, where the use of nanoprobes, nanochips, and nanodevices, microfluidic technology, lateral flow strips, etc.