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Hui-quan Li

Researcher at University of California, San Diego

Publications -  13
Citations -  384

Hui-quan Li is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microglia & Pinocytosis. The author has an hindex of 6, co-authored 10 publications receiving 286 citations. Previous affiliations of Hui-quan Li include Chinese Academy of Sciences & Zhejiang University.

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Journal ArticleDOI

Microglial migration mediated by ATP-induced ATP release from lysosomes

Ying Dou, +11 more
- 10 Jan 2012 - 
TL;DR: It is suggested that microglia respond to extracellular ATP by releasing ATP themselves through lysosomal exocytosis, thereby providing a positive feedback mechanism to generate a long-rangeextracellular signal for attracting distantmicroglia to migrate towards and accumulate at the site of injury.
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P2Y4 receptor-mediated pinocytosis contributes to amyloid beta-induced self-uptake by microglia.

Hui-quan Li, +10 more
- 01 Nov 2013 - 
TL;DR: The results demonstrate a previously unknown function of ATP as a “drink me” signal for microglia and P2Y4 receptors as a potential therapeutic target for the treatment of Alzheimer's disease.
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Neuronal activity regulates neurotransmitter switching in the adult brain following light-induced stress

Da Meng, +4 more
- 15 May 2018 - 
TL;DR: It is demonstrated that elevated activity of dopaminergic neurons in the paraventricular nucleus of the hypothalamus (PaVN) in the adult rat is required for the loss of dopamine expression after long-day photoperiod exposure, indicating homeostatic regulation of transmitter expression in the PaVN.
Journal ArticleDOI

Exercise enhances motor skill learning by neurotransmitter switching in the adult midbrain

Hui-quan Li, +1 more
- 04 May 2020 - 
TL;DR: It is suggested that neurotransmitter switching provides the basis by which sustained running benefits motor skill learning, presenting a target for clinical treatment of movement disorders.
Journal ArticleDOI

Analysis of microglial migration by a micropipette assay

Hang-jun Wu, +9 more
- 01 Feb 2014 - 
TL;DR: A protocol for rapidly triggering and monitoring microglial migration by using a micropipette assay that can be adopted to examine cell migration in multiple cell types, including cancer cells with a wide range of chemical signals.