Huige Li

TL;DR: Evidence is provided that independent mechanisms mediate the degradation of PON2 mRNA and protein after disturbance of Ca(2+) homoeostasis, which proposes that the underlying cause of ER stress determines the efficacy of putative cellular defence mechanisms.

TL;DR: The mechanisms of gut microbiota and its metabolites on immunometabolism are reviewed, recent findings on how the interaction between microbiota and polyphenol modulates host immunometabolicism are summarized, and future research directions are discussed.

TL;DR: This study provides direct evidence for a decreased whole body NO synthesis rate in healthy people with hypercholesterolemia.

TL;DR: The friend-and-foe role of dietary modification (including different diet styles, calorie restriction, and nutrient supplementation), as well as the potential benefits and concerns of physical activity and exercise on endothelium and oxidative stress, are discussed.

TL;DR: This review highlights the down-stream pathophysiology of noise-induced mental stress, which is based on an induction of inflammation and oxidative stress, and highlights noise-triggered uncoupling/dysregulation of endothelial and neuronal nitric oxide synthase and its central role for vascular dysfunction.