H
Hye Lim Kim
Researcher at University of Sydney
Publications - 1
Citations - 30
Hye Lim Kim is an academic researcher from University of Sydney. The author has contributed to research in topics: Voltage clamp & Receptor. The author has an hindex of 1, co-authored 1 publications receiving 20 citations.
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Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1.
Dinesh C. Indurthi,Elena Pera,Hye Lim Kim,Cindy Chu,Malcolm D. McLeod,J. Michael McIntosh,J. Michael McIntosh,Nathan L. Absalom,Mary Chebib +8 more
TL;DR: Using 2-electrode voltage clamp methods and maintaining a constant intracellular Ca(2+) concentration, this study observed a biphasic activation curve for ACh that is dependent on receptor stoichiometry and infer that there is an additional binding site for A Ch and Vc1.1 at the α9-α9 interface on the hypothesized (α9)₃(α10)⁂ nAChR.