Hye Won Lee

TL;DR: In this article, an enzyme-linked immunosorbent (ELI) assay was developed to measure human RBP4 plasma concentrations, which were then compared with various parameters related to insulin resistance in subjects with normal glucose tolerance (NGT; n = 57), impaired glucose tolerance and type 2 diabetes (n = 49).

TL;DR: In this article, a review of the recent development in microfluidics for medical diagnostics and integrations with biosensors is presented, focusing mainly on new developments in the last 5-10 years in materials development, chip architecture and integration, different sensing modes that can be used in conjunction with microfluidity, and new applications that have emerged or have been demonstrated; it also aims to point out where future research can be directed to in these areas.

TL;DR: The severity of glucose intolerance in women with pGDM is associated with high RBP4 and low adiponectin concentrations, which are inversely correlated with parameters of insulin resistance.

TL;DR: It is demonstrated that localized KillerRed activation in either the cell body or the axon triggers neuronal degeneration and death of the targeted cell, and targeting KillerRed to mitochondria results in organelle fragmentation without killing the cell, in contrast to the cell death observed when KillerRed is targeted to the plasma membrane.

TL;DR: This study eliminates the need for purification steps by detecting miRNA directly from raw cellular lysate using nonfouling polyethylene glycol microparticles and demonstrates the capability for multiplexing through analyzing the levels of three endogenous miRNAs in 3T3 cell lysates.