Y
Young Min Cho
Researcher at New Generation University College
Publications - 23
Citations - 4310
Young Min Cho is an academic researcher from New Generation University College. The author has contributed to research in topics: Type 2 diabetes & Type 2 Diabetes Mellitus. The author has an hindex of 20, co-authored 23 publications receiving 3986 citations. Previous affiliations of Young Min Cho include University of British Columbia & Seoul National University.
Papers
More filters
Journal ArticleDOI
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
Kazuki Yasuda,Kazuaki Miyake,Yukio Horikawa,Hara Kazuo,Haruhiko Osawa,Hiroto Furuta,Yushi Hirota,Hiroyuki Mori,Anna Jonsson,Yoshifumi Sato,Kazuya Yamagata,Kazuya Yamagata,Yoshinori Hinokio,He-Yao Wang,Toshihito Tanahashi,Naoto Nakamura,Yoshitomo Oka,Naoko Iwasaki,Yasuhiko Iwamoto,Yuichiro Yamada,Yuichiro Yamada,Yutaka Seino,Yutaka Seino,Hiroshi Maegawa,Atsunori Kashiwagi,Jun Takeda,Eiichi Maeda,Hyoung Doo Shin,Young Min Cho,Kyong Soo Park,Hong Kyu Lee,Maggie C.Y. Ng,Ronald C.W. Ma,Wing-Yee So,Juliana C.N. Chan,Valeriya Lyssenko,Tiinamaija Tuomi,Peter M. Nilsson,Leif Groop,Leif Groop,Naoyuki Kamatani,Akihiro Sekine,Yusuke Nakamura,Ken Yamamoto,Yoshida Teruhiko,Katsushi Tokunaga,Mitsuo Itakura,Hideichi Makino,Kishio Nanjo,Takashi Kadowaki,Masato Kasuga +50 more
TL;DR: The data implicate KCNQ1 as a diabetes susceptibility gene in groups of different ancestries as well as in two independent Japanese populations, and the risk allele of this polymorphism was associated with impairment of insulin secretion according to the homeostasis model assessment of β-cell function or the corrected insulin response.
Journal ArticleDOI
Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells.
Young Min Cho,Sujin Kwon,Youngmi Kim Pak,Hye Won Seol,Young Min Choi,Do Joon Park,Kyong Soo Park,Hong Kyu Lee +7 more
TL;DR: HESC differentiation was followed by dynamic changes in mitochondrial mass, ATP and ROS production, and antioxidant enzyme expressions, which led to a dramatic change in the expression of various antioxidant enzymes.
Journal ArticleDOI
Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes.
Young Min Cho,Byung-Soo Youn,Hye Won Lee,Namseok Lee,Sung-Shik Min,Soo Heon Kwak,Hong Kyu Lee,Kyong Soo Park +7 more
TL;DR: In this article, an enzyme-linked immunosorbent (ELI) assay was developed to measure human RBP4 plasma concentrations, which were then compared with various parameters related to insulin resistance in subjects with normal glucose tolerance (NGT; n = 57), impaired glucose tolerance and type 2 diabetes (n = 49).
Journal ArticleDOI
Differences in the glucose-lowering efficacy of dipeptidyl peptidase-4 inhibitors between Asians and non-Asians: a systematic review and meta-analysis
Yeong Gi Kim,Seokyung Hahn,Seokyung Hahn,Tae Jung Oh,Soo Heon Kwak,Kyong Soo Park,Young Min Cho +6 more
TL;DR: DPP-4 inhibitors exhibit a better glucose-lowering efficacy in Asians than in other ethnic groups; this requires further investigation to understand the underlying mechanism, particularly in relation to BMI.
Journal ArticleDOI
Resistin is secreted from macrophages in atheromas and promotes atherosclerosis.
Hye Seung Jung,Ki Ho Park,Young Min Cho,Young Min Cho,Sung Soo Chung,Hyun Ju Cho,Soo Youn Cho,Sang Joon Kim,Seong Yeon Kim,Hong Kyu Lee,Kyong Soo Park,Kyong Soo Park +11 more
TL;DR: Macrophages infiltrating atherosclerotic aneurysms secrete resistin, and resistin affects endothelial function and VSMC migration, and may contribute to atherogenesis by virtue of its effects on vascular endothelial cells and smooth muscle cells in humans.