Hyoungsu Kim

TL;DR: This work presents discrete, monodisperse, and precisely sizecontrollable core–shell mesoporous silica NPs smaller than 100 nm by using single Fe3O4 nanocrystals as cores (designated as Fe3 O4@mSiO2) and demonstrates the multifunctional bioapplications of the core-shell NPs for simultaneous magnetic resonance and fluorescence imaging, and for drug delivery.

TL;DR: In the in vivo T(1)-weighted magnetic resonance imaging (MRI), ESIONs showed longer circulation time than the clinically used gadolinium complex-based contrast agent, enabling high-resolution imaging and demonstrating the potential of ESions as T( 1) MRI contrast agents in clinical settings.

TL;DR: In vivo passive targeting and accumulation of the nanoparticles at the tumor sites was confirmed by both T2 MR and fluorescence imaging, and apoptotic morphology was clearly detected in tumor tissues of mice treated with DOX loaded nanocomposite nanoparticles, demonstrating that DOX was successfully delivered to the tumor Sites and its anticancer activity was retained.

TL;DR: M M U N I Nonblinking and Nonbleaching Upconverting Nanoparticles as an Optical Imaging Nanoprobe and T1 Magnetic Resonance Imaging Contrast Agent C A T IO N By Yong Il Park, Jeong Hyun Kim, Kang Taek Lee, Ki-Seok Jeon, Hyon Bin Na, Jung Ho Yu, Hyung Min Kim, Nohyun Lee, Seung Hong Choi, Sung-Il Baik, Hyoungsu Kim and Seung Pyo Park, Beom-Jin Park, Young Woon Kim

TL;DR: It is demonstrated that bioinert tantalum oxide nanoparticles are suitable nanoprobes for high-performance X-ray computed tomography (CT) imaging while simultaneously being cost-effective and meeting the criteria as a biomedical platform.