Nohyun Lee

TL;DR: This work presents discrete, monodisperse, and precisely sizecontrollable core–shell mesoporous silica NPs smaller than 100 nm by using single Fe3O4 nanocrystals as cores (designated as Fe3 O4@mSiO2) and demonstrates the multifunctional bioapplications of the core-shell NPs for simultaneous magnetic resonance and fluorescence imaging, and for drug delivery.

TL;DR: How MRI contrast effects can be improved by controlling the size, composition, doping, assembly, and surface properties of iron-oxide-based nanoparticles is discussed.

TL;DR: Magnetoresponsive Therapy Nohyun Lee, Dongwon Yoo, Daishun Ling,†,‡,⊥ Mi Hyeon Cho, Taeghwan H Yeon,*,†,† and Jinwoo Cheon.

TL;DR: In the in vivo T(1)-weighted magnetic resonance imaging (MRI), ESIONs showed longer circulation time than the clinically used gadolinium complex-based contrast agent, enabling high-resolution imaging and demonstrating the potential of ESions as T( 1) MRI contrast agents in clinical settings.

TL;DR: This Account discusses recent progress by this group and other researchers in the design and fabrication of multifunctional nanocomposite nanoparticles based on mesoporous silica nanostructures for applications to simultaneous diagnosis and therapy.