H
Hyung J. Shin
Researcher at Emory University
Publications - 5
Citations - 349
Hyung J. Shin is an academic researcher from Emory University. The author has contributed to research in topics: Biopsy & Respiratory disease. The author has an hindex of 3, co-authored 5 publications receiving 330 citations. Previous affiliations of Hyung J. Shin include University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: Final report
Edward S. Kim,Joe B. Putnam,Ritsuko Komaki,Garrett L. Walsh,Jae Y. Ro,Hyung J. Shin,Mylene T. Truong,Hojin Moon,S.G. Swisher,Frank V. Fossella,Fadlo R. Khuri,Waun Ki Hong,Dong M. Shin +12 more
TL;DR: The use of induction chemotherapy to optimize surgical resectability of thymoma followed by radiation therapy and consolidation chemotherapy lead to good control of residual disease and high overall survival rates is believed to prolongs lives and may cure locally advanced unresectable malignant thymomas.
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Phase II Study of a Liposome-Entrapped Cisplatin Analog (L-NDDP) Administered Intrapleurally and Pathologic Response Rates in Patients With Malignant Pleural Mesothelioma
Charles Lu,Roman Perez-Soler,Bilal Piperdi,Garrett L. Walsh,Stephen G. Swisher,W. Roy Smythe,Hyung J. Shin,Jae Y. Ro,Lei Feng,Mylene T. Truong,Adiseshu Yalamanchili,Gabriel Lopez-Berestein,Waun Ki Hong,Abdul R. Khokhar,Dong M. Shin +14 more
TL;DR: Intrapleural L-NDDP therapy in this patient population is feasible with significant but manageable toxicity, and pathologic responses are highly encouraging, although areas of mesothelioma that are not in direct communication with the pleural space will evade drug exposure and limit efficacy in some patients.
Journal Article
Synergistic tumor growth inhibition by combined treatment with green tea epigallocatechin-3-gallate (EGCG) and an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), erlotinib in squamous cell carcinoma of the head and neck (SCCHN)
Xin Zhang,John E. Lee,Mourad Tighiouart,Hyung J. Shin,Fadlo R. Khuri,Zhuo (Georgia) Chen,Dong M. Shin +6 more
TL;DR: Both the in vitro and in vivo results demonstrate significant anti-tumor activity for the combined treatment with EGCG and erlotinib, which provides a novel and promising chemopreventive regimen for SCCHN.
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Pathologic response with liposomal-entrapped cisplatin analog (L-NDDP) administered in patients (pts) with malignant pleural mesothelomia (MPM): Phase II clinical study
Dong M. Shin,Garrett L. Walsh,W.R Smythe,Jae Y. Ro,Hyung J. Shin,S.G. Swisher,Charles Lu,Frank V. Fossella,Fadlo R. Khuri,A Yalamanchili,Waun Ki Hong,Abdul R. Khokhar +11 more
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Role of cyclooxygenase-2 (COX-2) expression in tumor progression and survival in the squamous cell carcinoma of the head and neck (HNSCC)
M. S. Choe,Mourad Tighiouart,Andre Rogatko,Susan Muller,Hyung J. Shin,Marites Francisco,Vassiliki A. Papadimitrakopoulou,Fadlo R. Khuri,Waun Ki Hong,Zhengjia Chen,D. M. Shin +10 more
TL;DR: A large number of patients with premalignant lesions or HNSCC and normal epithelia of the head and neck from non-smokers without tumor were included and COX-2 expression was evaluated by immunohistochemistry on paraffin-embedded tissue and scored high.