scispace - formally typeset
I

I-Ju Liu

Researcher at Academia Sinica

Publications -  19
Citations -  1670

I-Ju Liu is an academic researcher from Academia Sinica. The author has contributed to research in topics: Epitope & Antibody. The author has an hindex of 9, co-authored 19 publications receiving 925 citations. Previous affiliations of I-Ju Liu include National Defense Medical Center & National Taiwan University.

Papers
More filters
Journal ArticleDOI

Development of therapeutic antibodies for the treatment of diseases

Ruei-Min Lu, +6 more
- 02 Jan 2020 - 
TL;DR: The preeminent antibody engineering technologies used in the development of therapeutic antibody drugs, such as humanization of monoclonal antibodies, phage display, the human antibody mouse, single B cell antibody technology, and affinity maturation are outlined.
Journal ArticleDOI

Advancement and applications of peptide phage display technology in biomedical science

Chien-Hsun Wu, +3 more
- 19 Jan 2016 - 
TL;DR: The latest technological advancements in the application of phage-displayed peptide libraries to applied biomedical sciences are summarized.
Journal ArticleDOI

Molecular Mimicry of Human Endothelial Cell Antigen by Autoantibodies to Nonstructural Protein 1 of Dengue Virus

I-Ju Liu, +5 more
- 18 Mar 2011 - 
TL;DR: DB16-1 targeted the same epitope in DV NS1 and LYRIC protein on human endothelial cells, suggesting that it might play a role in the pathogenesis of DHF/DSS.
Journal ArticleDOI

Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assay.

Hong-En Lin, +13 more
- 03 Jan 2012 - 
TL;DR: A dot blot assay is developed by using 67 alanine mutants of predicted surface-exposed E residues as a systematic approach to identify epitopes recognized by mAbs and polyclonal sera, which would further the understanding of humoral immune responses to DENV at the epitope level.
Journal ArticleDOI

Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells.

Kang-Hao Liang, +11 more
- 01 Oct 2018 - 
TL;DR: Analysis of colorectal cancer tissues showed that nuclear accumulation of EpICD was highly correlated with metastasis and poor prognosis, suggesting that it may play an important functional role in cancer progression.