Pi-Chun Li

TL;DR: The results indicate that the tumor-homing peptides can be used specifically target tumor vasculature and have the potential to improve the systemic treatment of patients with solid tumors.

TL;DR: A dot blot assay is developed by using 67 alanine mutants of predicted surface-exposed E residues as a systematic approach to identify epitopes recognized by mAbs and polyclonal sera, which would further the understanding of humoral immune responses to DENV at the epitope level.

TL;DR: Dengue virus serotype‐2 nonstructural protein‐1 antigens in both buffer system and human serum is evaluated, thus successfully achieving the first such use of these proteins as the target antigen for the development of diagnostic tools.

TL;DR: The use of SP5-2-conjugated liposomes enhances pharmacokinetic properties, improves efficacy and safety profiles, and allows for controlled biodistribution and drug release.

TL;DR: Identification and substitution of enhancing epitope as a novel strategy for developing safe dengue vaccines is supported and treatment with N8R-immunized sera reduced the enhancement of mortality in AG129 mice.