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Ian D. Pavord
Researcher at University of Oxford
Publications - 654
Citations - 55329
Ian D. Pavord is an academic researcher from University of Oxford. The author has contributed to research in topics: Asthma & Sputum. The author has an hindex of 108, co-authored 575 publications receiving 47691 citations. Previous affiliations of Ian D. Pavord include John Radcliffe Hospital & University of Warwick.
Papers
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Journal Article
Factors influencing the occurrence of airway hyperreactivity in the general population: the importance of atopy and airway calibre.
John Britton,Ian D. Pavord,K Richards,Alan J. Knox,A Wisniewski,I Wahedna,W. Kinnear,Anne E. Tattersfield,Scott T. Weiss +8 more
TL;DR: The independent effects of age, atopy, smoking and airway calibre, as well as reactivity to methacholine as the dose provoking a 20% fall in one-second forced expiratory volume, were assessed.
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Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines.
Maryam Salimi,Linda Stöger,W Liu,Simei Go,Ian D. Pavord,Paul Klenerman,Graham S. Ogg,Luzheng Xue +7 more
TL;DR: CysLTs, particularly LTE4, are important contributors to the triggering of human ILC2s in inflammatory responses, particularly when combined with other I LC2 activators.
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Aspergillus fumigatus during stable state and exacerbations of COPD
Mona Bafadhel,S McKenna,Joshua Agbetile,Abbie Fairs,Dhananjay Desai,Vijay Mistry,J. P. Morley,Mitesh Pancholi,Ian D. Pavord,Andrew J. Wardlaw,Catherine H. Pashley,Christopher E. Brightling +11 more
TL;DR: Assessments of lung function, allergen testing and sputum analysis for inflammation, bacteria and fungus were undertaken in COPD subjects and healthy smoking and nonsmoking controls and sensitisation to Aspergillus fumigatus was found to be related to poor lung function.
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Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability.
Christopher E. Brightling,W Monterio,Ruth H. Green,Debbie Parker,Mike Morgan,Andrew J. Wardlaw,Ian D. Pavord +6 more
TL;DR: In conclusion, sputum induction is safe and the cell and fluid phase mediators repeatable in the investigation of airway inflammation in patients with COPD and VAS symptom scores and the CRQ are reproducible outcome measures in COPD.
Journal ArticleDOI
Quantitative computed tomography-derived clusters: redefining airway remodeling in asthmatic patients.
Sunil Gupta,Sunil Gupta,Ruth Hartley,Umair T. Khan,Amisha Singapuri,B Hargadon,W Monteiro,Ian D. Pavord,Ana R. Sousa,Richard P. Marshall,Deepak Subramanian,David G. Parr,James Entwisle,Salman Siddiqui,Vimal Raj,Christopher E. Brightling +15 more
TL;DR: Quantitative CT analysis provides a new perspective in asthma phenotyping, which might prove useful in patient selection for novel therapies, and three novel, quantitative, CT-determined asthma phenotypes were identified.