S
Salman Siddiqui
Researcher at University of Leicester
Publications - 172
Citations - 6501
Salman Siddiqui is an academic researcher from University of Leicester. The author has contributed to research in topics: Asthma & Population. The author has an hindex of 36, co-authored 160 publications receiving 4960 citations. Previous affiliations of Salman Siddiqui include Glenfield Hospital & University Hospitals of Leicester NHS Trust.
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Journal ArticleDOI
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
David F. Choy,Kevin M. Hart,Lee A. Borthwick,Aarti Shikotra,Deepti R. Nagarkar,Salman Siddiqui,Guiquan Jia,Chandra M. Ohri,Emma Doran,Emma Doran,Kevin M. Vannella,Claire A. Butler,Beverley Hargadon,Joshua Sciurba,Richard L. Gieseck,Robert W. Thompson,Sandra White,Alexander R. Abbas,Janet Jackman,Lawren C. Wu,Jackson G. Egen,Liam G Heaney,Thirumalai R. Ramalingam,Joseph R. Arron,Thomas A. Wynn,Peter Bradding +25 more
TL;DR: It is demonstrated that asthma can be divided into three immunological clusters: TH2-high, TH17- high, and TH2/17- low, and the data suggest that combination therapies targeting both pathways may better treat asthmatic individuals.
Journal ArticleDOI
Expression of the T Helper 17-Associated Cytokines IL-17A and IL-17F in Asthma and COPD
Camille Doe,Mona Bafadhel,Salman Siddiqui,Dhananjay Desai,Vijay Mistry,Paul Rugman,M McCormick,Joanne Woods,Richard D. May,Matthew A. Sleeman,I.K. Anderson,Christopher E. Brightling +11 more
TL;DR: The findings support a potential role for the Th17 cytokines IL-17A andIL-17F in asthma and COPD, but do not demonstrate a relationship with neutrophilic inflammation.
Journal ArticleDOI
Blood Eosinophils: A Biomarker of Response to Extrafine Beclomethasone/Formoterol in Chronic Obstructive Pulmonary Disease
Salman Siddiqui,Alessandro Guasconi,Jørgen Vestbo,Paul W. Jones,Alvar Agusti,Pierluigi Paggiaro,Jadwiga A. Wedzicha,Dave Singh +7 more
TL;DR: The hypothesis that treatment differences in patients with severe COPD with a history of exacerbations differ according to the baseline blood eosinophil count is evaluated by performing a post hoc analysis on the FORWARD study data.
Journal ArticleDOI
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Rachael A. Evans,Hamish McAuley,Ewen M Harrison,Aarti Shikotra,Amisha Singapuri,Marco Sereno,Omer Elneima,Annemarie B Docherty,Nazir I Lone,Nazir I Lone,Olivia C. Leavy,Luke Daines,J Kenneth Baillie,J Kenneth Baillie,Jeremy S. Brown,Trudie Chalder,Anthony De Soyza,Nawar Diar Bakerly,Nawar Diar Bakerly,Nicholas Easom,John R. Geddes,John R. Geddes,Neil J. Greening,Nicholas Hart,Liam G Heaney,Liam G Heaney,Simon Heller,Luke Howard,John R. Hurst,Joseph Jacob,R. Gisli Jenkins,Caroline J. Jolley,Steven Kerr,Onn Min Kon,Onn Min Kon,Keir Lewis,Janet M. Lord,Gerry P McCann,Stefan Neubauer,Peter J. M. Openshaw,Dhruv Parekh,Dhruv Parekh,Paul E Pfeffer,Paul E Pfeffer,Najib M. Rahman,Betty Raman,Matthew Richardson,Matthew J. Rowland,Malcolm G Semple,Malcolm G Semple,Ajay M. Shah,Sally J Singh,Aziz Sheikh,David B. Thomas,Mark Toshner,James D. Chalmers,Ling-Pei Ho,Alex Horsley,Michael Marks,Michael Marks,Krisnah Poinasamy,Louise V. Wain,Christopher E. Brightling,Kathryn M. Abel,Huzaifa Adamali,Davies Adeloye,O Adeyemi,F Adeyemi,S Ahmad,R Ahmed,M Ainsworth,A Alamoudi,M Aljaroof,Louise Allan,R Allen,A Alli,B Al-Sheklly,D Altmann,Denise Anderson,M Andrews,A Angyal,Charalambos Antoniades,Gill Arbane,Cherie Armour,N Armstrong,Lynne Armstrong,H Arnold,David T Arnold,Milton Ashworth,A Ashworth,H Assefa-Kebede,P Atkin,H Atkins,A Atkins,R Aul,C Avram,R Baggott,D Baguley,J K Baillie,S Bain,M Bakali,M Bakau,Emma Baldry,David R Baldwin,Clive Ballard,J Bambrough,Ruth E Barker,Shaney L Barratt,F Barrett,N Basu,Rachel L. Batterham,H Baxendale,Hannah Bayes,M Bayley,Michael Beadsworth,P Beirne,R Bell,Derek Bell,Colin Berry,S Betts,K Bhui,L Bishop,J Blaikely,C Bloomfield,A Bloss,A Bolger,C E Bolton,J Bonnington,A Botkai,M Bourne,C Bourne,E Bradley,K Bramham,L Brear,Gerome Breen,J Breeze,A Briggs,E Bright,C E Brightling,Simon E. Brill,K Brindle,L Broad,M Broome,J S Brown,Matthew A. Brown,Jamie Brown,Richard G. Brown,V Brown,Ashley C. Brown,Traolach S. Brugha,Nigel J. Brunskill,M Buch,A Bularga,Edward T. Bullmore,David J. Burn,G Burns,Jonathan P. Busby,A.J. Buttress,S Byrne,P Cairns,P C Calder,E Calvelo,B Card,L Carr,Gail Carson,Patrice Carter,J Cavanagh,T Chalder,J D Chalmers,Rachel C. Chambers,Keith M. Channon,Kath Chapman,A Charalambou,N Chaudhuri,A Checkley,J Chen,L Chetham,E R Chilvers,H Chinoy,K Chong-James,N Choudhury,G Choudhury,P Chowdhury,P Chowienczyk,C Christie,David W. Clark,C. Clark,Judith Clarke,P Clift,Sara Clohisey,Z Coburn,John B. Cole,C Coleman,D W Connell,B Connolly,Lynda Connor,Angela Cook,Brendan G Cooper,C Coupland,T Craig,P Crisp,D. Cristiano,M G Crooks,A Cross,I Cruz,Paul Cullinan,L Daines,M Dalton,Paul Dark,J. Dasgin,Asaf David,C David,Melanie J. Davies,Gail Davies,Kevin A. Davies,F. Davies,G A Davies,Enya Daynes,T I de Silva,A De Soyza,Bill Deakin,A Deans,S Defres,Anne Dell,K Dempsey,Joe Dennis,A Dewar,R Dharmagunawardena,N Diar Bakerly,A Dipper,S Diver,S N Diwanji,M Dixon,R Djukanovic,H Dobson,C Dobson,S L Dobson,A B Docherty,Andrew Donaldson,T Dong,N. Dormand,A Dougherty,R Dowling,S Drain,P Dulawan,S Dunn,N Easom,C Echevarria,Sebastian Edwards,Charlotte L. Edwardson,B Elliott,Amanda F. Elliott,Y Ellis,A Elmer,O Elneima,R A Evans,Julie Evans,H Evans,David M. Evans,R I Evans,R Evans,Todd Evans,L Fabbri,S Fairbairn,A Fairman,K Fallon,D Faluyi,C Favager,Timothy Felton,Jonathan Finch,S Finney,Helen L. Fisher,Shelley Fletcher,R Flockton,D Foote,A Ford,D Forton,Richard W. Francis,S Francis,C Francis,A Frankel,E Fraser,R Free,N French,J Fuld,James J Furniss,L Garner,Nikki Gautam,J R Geddes,P M George,Jeremy George,M Gibbons,L Gilmour,Fergus V. Gleeson,J Glossop,S Glover,N Goodman,B Gooptu,T. Gorsuch,E Gourlay,P Greenhaff,William Greenhalf,A Greenhalgh,N J Greening,John P Greenwood,S Greenwood,R Gregory,Douglas Grieve,M. Gummadi,Atul Gupta,S Gurram,Ellen Guthrie,K Hadley,A Haggar,K Hainey,P Haldar,I Hall,Lynsey S. Hall,M Halling-Brown,R Hamil,N A Hanley,Hayley Hardwick,Elaine Hardy,B Hargadon,Kyle Harrington,V Harris,E M Harrison,Phil Harrison,N Hart,Alison G. Harvey,Miriam Harvey,M Harvie,M Havinden-Williams,J Hawkes,N Hawkings,J Haworth,A Hayday,L G Heaney,J L Heeney,Melissa Heightman,S Heller,Morag Henderson,L Hesselden,Toby Hillman,Aroon D. Hingorani,T Hiwot,L P Ho,A Hoare,M Hoare,P Hogarth,A Holbourn,L Holdsworth,D Holgate,K Holmes,B Holroyd-Hind,A Horsley,A Hosseini,Matthew Hotopf,L Houchen,Louise M. Howard,A Howell,E Hufton,Alan Hughes,Joseph Hughes,R Hughes,A Humphries,N Huneke,J R Hurst,R Hurst,Mujtaba Husain,T Hussell,W Ibrahim,A Ient,L Ingram,Khalida Ismail,Thomas A Jackson,J Jacob,W Y James,Sam M. Janes,H Jarvis,B Jayaraman,R G Jenkins,Peter Jezzard,K Jiwa,Sonia Johnson,Craig Johnson,D Johnston,C Jolley,C J Jolley,Ifan Jones,S Jones,D Jones,H Jones,Graeme Jones,Margaret Jones,S. Jose,Thomas Kabir,G Kaltsakas,Vicky Kamwa,P Kar,Z Kausar,Siobhan Kelly,S Kerr,A L Key,F Khan,Kamlesh Khunti,C King,B King,P Kitterick,Paul Klenerman,L Knibbs,Stephen R Knight,A Knighton,O M Kon,S Kon,S S Kon,Ania Korszun,Christos P Kotanidis,I Koychev,P Kurupati,J Kwan,C Laing,H Lamlum,Geraldine Landers,Claudia Langenberg,Daniel Lasserson,Alison M. Lawrie,A Lea,O C Leavy,Donghyung Lee,E Lee,K Leitch,R Lenagh,K Lewis,V Lewis,K E Lewis,J Lewis,N Lewis-Burke,Teresa Light,L Lightstone,L Lim,S Linford,A Lingford-Hughes,Marc Lipman,K. Liyanage,A Lloyd,S Logan,David A. Lomas,N I Lone,R. Loosley,J M Lord,H Lota,A Lucey,G MacGowan,I Macharia,Clare E. Mackay,Linda MacLiver,Shyam Madathil,G Madzamba,N Magee,N Mairs,N Majeed,E Major,M Malim,G Mallison,W Man,Swapna Mandal,K Mangion,P Mansoori,S Marciniak,M Mariveles,M Marks,Ben G. Marshall,A Martineau,Nick A Maskell,D Matila,L Matthews,J Mayet,S McAdoo,H McAllister-Williams,P McArdle,A McArdle,D McAulay,H McAuley,Daniel F. McAuley,K McCafferty,G P McCann,H McCauley,P McCourt,L Mcgarvey,J McGinness,A McGovern,H. McGuinness,Iain B. McInnes,K McIvor,E McIvor,Alex D. McMahon,M J McMahon,L. McMorrow,T Mcnally,M McNarry,A McQueen,Helen McShane,S Megson,J Meiring,Donna J. Menzies,A Michael,L Milligan,N Mills,James E. Mitchell,A Mohamed,Philip L. Molyneaux,William Monteiro,A Morley,L Morrison,R Morriss,Ardythe L. Morrow,A Moss,A J Moss,Paul Moss,Elizabeta B. Mukaetova-Ladinska,U Munawar,Elodie Murali,J Murira,H Nassa,P Neill,S Neubauer,David E. Newby,H Newell,A Newton Cox,Timothy R Nicholson,D Nicoll,Claire M. Nolan,M J Noonan,P. Novotny,J Nunag,J Nyaboko,L. O'Brien,N Odell,G Ogg,O Olaosebikan,C Oliver,Z. Omar,Peter J. M. Openshaw,P Rivera-Ortega,R Osbourne,Marlies Ostermann,C Overton,J Oxton,E Pacpaco,S Paddick,Padmasayee Papineni,K Paradowski,M Pareek,D Parekh,H Parfrey,Carmine M. Pariante,Stephen C. J. Parker,Margot W. Parkes,J Parmar,R Parvin,S Patale,Brij Patel,Smitaa Patel,Meenal Patel,B Pathmanathan,Michael Pavlides,J E Pearl,Daniel Peckham,J. Pendlebury,Y Peng,Catherine Pennington,I Peralta,E. Perkins,T Peto,Nayia Petousi,John R. Petrie,P Pfeffer,J Phipps,Jonathan Pimm,K Piper Hanley,R Pius,S Plein,T Plekhanova,K Poinasamy,Oliver Polgar,L Poll,J C Porter,S Portukhay,N Powell,L Price,David Price,Anthony N. Price,C. Price,A Prickett,S. Quaid,J Quigley,Jennifer K Quint,H Qureshi,N Rahman,M Rahman,M Ralser,B Raman,A Ramos,J Rangeley,Tim Rees,K Regan,Alexander Richards,M Richardson,E Robertson,J Rodgers,G Ross,J Rossdale,Anthony J. Rostron,A Routen,A Rowland,M J Rowland,J Rowland,S L Rowland-Jones,K Roy,Igor Rudan,R Russell,E. Russell,R Sabit,E K Sage,Nilesh J. Samani,R Samuel,E Sapey,D Saralaya,A Saratzis,Jack A. Sargeant,T Sass,Naveed Sattar,Kathryn J Saunders,R Saunders,W Saxon,Avan Aihie Sayer,W Schwaeble,Janet T Scott,K Scott,N Selby,Malcolm G Semple,M Sereno,Khalid Shah,A. J. Shah,P Shah,Manu Sharma,Michael Sharpe,C Sharpe,V Shaw,A Sheikh,K Shevket,A Shikotra,Jennifer M. Short,Salman Siddiqui,Louise Sigfrid,G Simons,J Simpson,A Singapuri,S J Singh,C Singh,S Singh,J Skeemer,I Smith,Jennifer A. Smith,Lee B. Smith,Andrew Smith,Marcia Soares,D Southern,M Spears,L G Spencer,F Speranza,Louise Stadon,S Stanel,Michael C Steiner,David J. Stensel,M Stern,Isobel D. Stewart,James Stockley,Richard Kevin Stone,A Storrie,K Storton,E Stringer,Christian P Subbe,Cathie Sudlow,Z Suleiman,Charlotte Summers,C Summersgill,D Sutherland,D L Sykes,Robert Sykes,Nick P. Talbot,A L Tan,Clare J Taylor,Andrew M. Taylor,A Te,H Tedd,C J Tee,H. Tench,S Terry,S Thackray-Nocera,F Thaivalappil,D Thickett,David C. Thomas,D C Thomas,Aliki Thomas,Alfred A.R. Thompson,Teresa Thompson,T Thornton,Ryan S Thwaites,Mark J. Tobin,G F Toingson,C Tong,M Toshner,Rhian M. Touyz,K A Tripp,Elizabeth M. Tunnicliffe,E Turner,L Turtle,H Turton,R Ugwuoke,R Upthegrove,J Valabhji,K Vellore,E Wade,L V Wain,L O Wajero,S Walder,Susan P. Walker,E Wall,T Wallis,S Walmsley,S Walsh,Jill Walsh,L Watson,JM Watson,E. Watson,Carly Welch,H Welch,B. Welsh,Simon Wessely,S West,H Wheeler,V Whitehead,J Whitney,S Whittaker,B Whittam,J Wild,M Wilkins,D Wilkinson,Nicola Williams,Bryan Williams,Julie Williams,S A Williams-Howard,M Willicombe,G Willis,David Wilson,I Wilson,N Window,Miles D. Witham,R. Wolf-Roberts,F Woodhead,J Woods,Daniel G. Wootton,J Worsley,D Wraith,L Wright,C Wright,S Wright,C Xie,S Yasmin,Thomas Yates,K P Yip,B Young,S Young,A Young,A J Yousuf,A Yousuf,A Zawia,B Zhao,O. Zongo +780 more
TL;DR: In this paper, the effects of COVID-19-related hospitalisation on health and employment, to identify factors associated with recovery, and to describe recovery phenotypes were determined.
Journal ArticleDOI
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial.
Phillip Monk,Richard J Marsden,Victoria Tear,Jody Brookes,Toby N Batten,Marcin Mankowski,Felicity J Gabbay,Donna E. Davies,Stephen T. Holgate,Stephen T. Holgate,Ling-Pei Ho,Tristan W Clark,Ratko Djukanovic,Tom Wilkinson,Michael G. Crooks,Davinder Dosanjh,Salman Siddiqui,Najib M. Rahman,Jacklyn A Smith,Alex Horsley,Tim Harrison,Dinesh Saralaya,Lorcan McGarvey,Alastair Watson,Edmund Foster,Adam Fleet,Dave Singh,Sophie Hemmings,Sandra Aitken,Sarah Dudley,Rona Beegan,Angela Thompson,Pedro Mb Rodrigues +32 more
TL;DR: Patients who received SNG001 had greater odds of improvement and recovered more rapidly from SARS-CoV-2 infection than patients who received placebo, providing a strong rationale for further trials.