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Ian D. Pavord
Researcher at University of Oxford
Publications - 654
Citations - 55329
Ian D. Pavord is an academic researcher from University of Oxford. The author has contributed to research in topics: Asthma & Sputum. The author has an hindex of 108, co-authored 575 publications receiving 47691 citations. Previous affiliations of Ian D. Pavord include John Radcliffe Hospital & University of Warwick.
Papers
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Journal ArticleDOI
The use of induced sputum to investigate airway inflammation.
TL;DR: The development over the last eight years of new and reliable techniques to assess airway need to perform the inductions carefully are described, at the expense of increased adverse effects including mild bronchoconstriction.
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Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies.
Hector Ortega,Steven W. Yancey,Bhabita Mayer,Necdet B Gunsoy,Oliver N. Keene,Eugene R. Bleecker,Christopher E. Brightling,Ian D. Pavord +7 more
TL;DR: An analysis of data from two randomised, double-blind, placebo-controlled studies of at least 32 weeks duration has shown a close relationship between baseline blood eosinophil count and clinical efficacy of mepolizumab in patients with severe eOSinophilic asthma and a history of exacerbations.
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Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial
R Siva,Ruth H. Green,Christopher E. Brightling,M. Shelley,B Hargadon,S McKenna,W Monteiro,Mike A. Berry,D Parker,Andrew J. Wardlaw,Ian D. Pavord +10 more
TL;DR: A management strategy that aims to minimise eosinophilic airway inflammation, as well as symptoms, is associated with a reduction in severe exacerbations of chronic obstructive pulmonary disease.
Journal ArticleDOI
Safety and Efficacy of Bronchial Thermoplasty in Symptomatic, Severe Asthma
Ian D. Pavord,Gerard Cox,Neil C. Thomson,Adalberto Sperb Rubin,Paul A. Corris,Robert Niven,Kian Fan Chung,Michel Laviolette +7 more
TL;DR: Bronchial thermoplasty is associated with a short-term increase in asthma-related morbidity, however, there is preliminary evidence of long-lasting improvement in asthma control.
Journal ArticleDOI
Exhaled nitric oxide in pulmonary diseases: a comprehensive review.
Peter J. Barnes,Raed A. Dweik,Arthur F. Gelb,Peter G. Gibson,Steven C. George,Hartmut Grasemann,Ian D. Pavord,Felix Ratjen,Philip E. Silkoff,D. Robin Taylor,Noe Zamel +10 more
TL;DR: Monitoring FeNO in pulmonary hypertension and cystic fibrosis has opened up a window to the role NO may play in their pathogenesis and possible clinical benefits in the management of these diseases.