Showing papers by "Ignatius Tak-sun Yu published in 2018"
TL;DR: The incidences of colon and rectal cancers have exhibited divergent patterns between 1983 and 2012 in Hong Kong, indicating heterogeneous etiologies between these two types of cancers.
Abstract: Colorectal cancer has been the second most common cancer among men and women in Hong Kong since 2012, but the underlying reasons for this increase remain unclear. We describe the incidence trend for colorectal cancer in Hong Kong to explore its etiology within this population. The temporal trends in colorectal cancer incidence between 1983 and 2012 were analyzed with joinpoint regressions by sex, age groups, and anatomic sites among adults using data from the Hong Kong Cancer Registry. An age-period-cohort analysis was used to evaluate the effects of age, calendar periods, and birth cohorts on the observed temporal trends. The incidence of colon cancer among those aged 50 years and older in both sexes increased steadily from 1983 until the mid-1990s and was followed by a slight decrease thereafter, whereas the incidence among those aged 20–49 years decreased steadily from 1983 to 2012. In contrast, the incidence of rectal cancer steadily increased in men and remained stable in women throughout the study period. Significant period and birth cohort effects were observed for colon cancer, whereas period effects on the temporal trends were observed for male rectal cancer. The incidences of colon and rectal cancers have exhibited divergent patterns between 1983 and 2012 in Hong Kong, indicating heterogeneous etiologies between these two types of cancers. Surveillance of the risk factors related to colon and rectal cancers in the Hong Kong population should be performed, and the increased rectal cancer incidence in males is worthy of extra attention.
13 citations
TL;DR: There is perceived value of DM from the perspective of employees, especially with respect to its value for coworkers, and Rehabilitation efforts should continue to focus attention on the value of disability management (DM).
Abstract: Purpose: To provide an international analysis of employees’ views of the influence of disability management (DM) on the workplace.Methodology: An international research team with representation fro...
7 citations
TL;DR: Household cleaning products are widely used by the public, but limited data have been obtained on whether their use induces allergic dermatitis in children.
Abstract: Background
Household cleaning products are widely used by the public, but limited data have been obtained on whether their use induces allergic dermatitis in children.
Objective
This study investigated the association between exposure to household cleaning products and allergic dermatitis in primary-school children.
Methods
A prospective cohort study of Hong Kong primary-school children was conducted between 2012 and 2014. A baseline survey was administered to 1,812 students who did not have allergic dermatitis. Information on respiratory symptoms, exposure to household chemical cleaning products and other topics was collected using a self-designed questionnaire. A cumulative chemical burden (CCB) score was calculated for each student by summing the duration of exposure to 14 chemical cleaning products. Principal component analysis was used to identify patterns in the use of these cleaning products. Logistic regression was performed to calculate relative risk (RR) with 95% confidence intervals (CIs) after adjusting for potential confounders.
Results
Eighty-nine (4.9%) of the students surveyed had dermatitis during the follow-up. However, exposure to individual chemical cleaning products was not found to be associated with the children's allergic dermatitis (all P > 0.05). In contrast to those in the lowest tertile, neither CCB scores in the middle tertile (RR: 1.16, 95% CI: 0.67 to 2.00) nor those in the highest tertile (RR: 1.24, 95% CI: 0.73 to 2.14) were significantly associated with the risk of allergic dermatitis. The adjusted RR for every 5-unit increment in CCB score was 1.01 (95% CI: 0.98 to 1.03). Four patterns of cleaning-product use were derived, but none were found to be associated with the risk of dermatitis (all P > 0.05).
Conclusion
The use of household chemical cleaning products is not associated with the risk of dermatitis in primary-school children.
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3 citations