Ik-Kyung Jang

TL;DR: This chapter reviews the early history of OCT development with an emphasis on basic concepts and the process of technology translation, as well as advances in imaging speed using swept source/Fourier domain detection.

TL;DR: Seasonal variations in the incidence of ACS reflect differences in the underlying pathobiology, with the proportion of plaque rupture highest in winter, whereas that of plaque erosion is highest in summer.

TL;DR: Patients with healed plaque in the culprit vessel had a higher incidence of revascularization, as compared to those without healed plaque, at 2 years, and presence of layered plaque and low-density lipoprotein cholesterol levels were independently associated with an increased risk ofRevascularization.

TL;DR: OCT confirms that female gender is associated with a greater than twofold increased risk of developing proximal coronary edge dissections as compared to men and the most potent independent predictor of proximal artery edge dissection is the presence of a proximal lipid rich plaque.

TL;DR: Although the factors for future cardiac events were identified, all 3 predictors are related to plaque burden, so radiofrequency intravascular ultrasound was used in the PROSPECT trial and showed that plaque burden >70%, virtual histology-thin–cap fibroatheroma, and minimal luminal area ≤4.0 mm2 are factors for composite major adverse cardiac events during the 3-year follow-up period.