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In Sook Kwun
Researcher at Andong National University
Publications - 9
Citations - 190
In Sook Kwun is an academic researcher from Andong National University. The author has contributed to research in topics: Leptin & Adipogenesis. The author has an hindex of 7, co-authored 9 publications receiving 173 citations.
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Green tea catechin enhances cholesterol 7α-hydroxylase gene expression in HepG2 cells
TL;DR: The results suggest that the expression of the CYP7A1 gene may be directly regulated by green tea catechins at the transcriptional level.
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Eicosapentaenoic acid increases lipolysis through up-regulation of the lipolytic gene expression and down-regulation of the adipogenic gene expression in 3T3-L1 adipocytes.
TL;DR: It is suggested that EPA may modulate lipid metabolism by stimulation oflipolysis, which was associated with induction of lipolytic gene expression and suppression of adipogenic gene expression in 3T3-L1 adipocytes.
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Marginal zinc deficiency in rats decreases leptin expression independently of food intake and corticotrophin-releasing hormone in relation to food intake
TL;DR: Leptin gene expression in epididymal white adipose tissue, hypothalamic corticotropin-releasing hormone, and hypothalamic neuropeptide Y of rats Zn-deficient only to show reduced food intake and growth rate but not food intake cycling are likely responding to reducedFood intake caused by Zn deficiency.
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Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling
TL;DR: Results showed that chronic zinc deprivation accelerated VSMC proliferation, perhaps due to down-regulation of MAPK-JNK signaling, and that the anti-cell proliferative role of zinc is VSMC-specific, and suggested that zinc may have anti-VSMC proliferative properties in atherosclerosis.
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Leptin gene expression and serum leptin levels in zinc deficiency: implications for appetite regulation in rats.
Soo Lim Lee,Eun Hee Kwak,Yang Ha Kim,Je-Yong Choi,Soon Tae Kwon,John H. Beattie,In Sook Kwun +6 more
TL;DR: Increased leptin levels in linguinal adipocytes is consistent with the expected physiological change of a decrease in appetite under Zn deficiency, but before coming to any firm conclusion, further studies on adipose tissue-specific leptin expression are necessary for clarifying the cause of lower appetite in zinc deficiency.