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Inbal Shamir
Researcher at Hebrew University of Jerusalem
Publications - 6
Citations - 146
Inbal Shamir is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Epigenomics & Bookmarking. The author has an hindex of 4, co-authored 5 publications receiving 113 citations.
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Journal ArticleDOI
The p53 C Terminus Controls Site-Specific DNA Binding and Promotes Structural Changes within the Central DNA Binding Domain
Oleg Laptenko,Idit Shiff,William A. Freed-Pastor,Andrew Zupnick,Melissa Mattia,Ella Freulich,Inbal Shamir,Noam Kadouri,Tamar Kahan,James J. Manfredi,Itamar Simon,Carol Prives +11 more
TL;DR: The results provide several unanticipated and interconnected findings that enable stable formation of p53-DNA complexes to divergent binding sites via DNA-induced conformational changes within the DBD itself.
Journal ArticleDOI
Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns.
Elisheva Javasky,Inbal Shamir,Shashi Gandhi,Shawn Egri,Oded Sandler,Scott B. Rothbart,Noam Kaplan,Jacob D. Jaffe,Alon Goren,Alon Goren,Itamar Simon +10 more
TL;DR: Evidence is provided to support a model where histone modifications may play a role in mitotic bookmarking and uncovers new insights into the deposition of nucleosomes during mitosis.
Journal ArticleDOI
Biases in the SMART-DNA library preparation method associated with genomic poly dA/dT sequences.
TL;DR: This analysis demonstrates that sequenced reads originating from SMART-DNA libraries are heavily skewed toward genomic poly dA/dT tracts, and needs to be considered when deciding to use SMART based technology for library preparation.
Posted ContentDOI
Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns
Elisheva Javasky,Inbal Shamir,Shashi Gandhi,Shawn Egri,Oded Sandler,Scott B. Rothbart,Noam Kaplan,Jacob D. Jaffe,Alon Goren,Itamar Simon +9 more
TL;DR: This study provides evidence to support a model where mitotic bookmarking is achieved by histone modifications, and uncovers new insights into the deposition of nucleosomes during mitosis.
Posted ContentDOI
Study of the mitotic chromatin shows involvement of histone modifications in bookmarking and reveals nucleosome deposition patterns
Elisheva Javasky,Inbal Shamir,Shashi Gandhi,Shawn Egri,Oded Sandler,Noam Kaplan,Jacob D. Jaffe,Alon Goren,Itamar Simon +8 more
TL;DR: The results demonstrate that the epigenomic landscape can serve as a major component of the mitotic bookmarking process, and provide evidence for a mitotic deposition and deacetylation of the nucleosomes surrounding the NDR.