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Ines Tomoco Kusumoto
Researcher at Cairo University
Publications - 12
Citations - 849
Ines Tomoco Kusumoto is an academic researcher from Cairo University. The author has contributed to research in topics: Reverse transcriptase & HIV-1 protease. The author has an hindex of 8, co-authored 12 publications receiving 808 citations.
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Screening of various plant extracts used in ayurvedic medicine for inhibitory effects on human immunodeficiency virus type 1 (HIV-1) protease
Ines Tomoco Kusumoto,Takeshi Nakabayashi,Hiroaki Kida,Hirotsugu Miyashiro,Masao Hattori,Tsuneo Namba,Kunitada Shimotohno +6 more
TL;DR: One of them, arecatannin B1 showed significant HIV‐1‐PR inhibitory activity and was shown by the A. catechu extract, from which some procyanidins were isolated.
Journal ArticleDOI
Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase
Sahar El-Mekkawy,Meselhy R. Meselhy,Ines Tomoco Kusumoto,Shigetoshi Kadota,Masao Hattori,Tsuneo Namba +5 more
TL;DR: The stereochemistry of 1 was established in this paper by nuclear magnetic resonance spectroscopy and was non-competitive with respect to the substrate but competitive withrespect to a template-primer.
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Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans
TL;DR: Extracts of green tea and black tea, and polyphenol mixtures showed appreciable inhibition in the synthesis of insoluble glucan, and theaflavin and its mono- and digallates had potent inhibitory activities at concentrations of 1-10 mM against GTF.
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Screening of Indonesian plant extracts for anti‐human immunodeficiency virus—type 1 (HIV‐1) activity
Toru Otake,Haruyo Mori,Motoko Morimoto,Noboru Ueba,Supriyatna Sutardjo,Ines Tomoco Kusumoto,Masao Hattori,Tsuneo Namba +7 more
TL;DR: Of 30 Indonesian plant extracts tested for their human immunodeficiency virus type‐1 (HIV‐1) inhibitory activities, six were shown to be effective by assays using HIV‐1‐infected MT‐4 cells: a methanol extract of mahoni and water extracts of benalu teh, which showed a significant inhibition of HIV‐ 1 protease.
Journal ArticleDOI
Inhibitory effects of indonesian plant extracts on reverse transcriptase of an RNA Tumour Virus (I)
Ines Tomoco Kusumoto,I. Shimada,Nobuko Kakiuchi,Masao Hattori,Tsuneo Namba,Sutardjo Supriyatna +5 more
TL;DR: Indonesian medicinal plants extracts tested for inhibitory activity on avian myeloblastosis virus showed no appreciable cytotoxicity at concentrations where over 90% of RT activity was inhibited.