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Inga Hegemann
Researcher at University of Zurich
Publications - 20
Citations - 729
Inga Hegemann is an academic researcher from University of Zurich. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 6, co-authored 16 publications receiving 488 citations. Previous affiliations of Inga Hegemann include University of St. Gallen.
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Journal ArticleDOI
Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy
K. John Pasi,Savita Rangarajan,Pencho Georgiev,Tim Mant,Michael Desmond Creagh,Toshko Lissitchkov,David H. Bevan,Steve Austin,Charles R. M. Hay,Inga Hegemann,Rashid S. Kazmi,Pratima Chowdary,Liana Gercheva-Kyuchukova,Vasily Mamonov,Margarita Timofeeva,Chang-Heok Soh,Pushkal Garg,Akshay Vaishnaw,Akin Akinc,Benny Sørensen,Margaret V. Ragni +20 more
TL;DR: Once‐monthly subcutaneous administration of fitusiran resulted in dose‐dependent lowering of the antithrombin level and increased thrombin generation in participants with hemophilia A or B who did not have inhibitory alloantibodies.
Journal ArticleDOI
Effect of ultra-short-term treatment of patients with iron deficiency or anaemia undergoing cardiac surgery: a prospective randomised trial
Donat R. Spahn,Felix Schoenrath,Gabriela H. Spahn,Burkhardt Seifert,Philipp Stein,Oliver M. Theusinger,Alexander Kaserer,Inga Hegemann,Axel Hofmann,Axel Hofmann,Francesco Maisano,Volkmar Falk +11 more
TL;DR: An ultra-short-term combination treatment with intravenous iron, subcutaneous erythropoietin alpha, vitamin B12, and oral folic acid reduced RBC and total allogeneic blood product transfusions in patients with preoperative anaemia or isolated iron deficiency undergoing elective cardiac surgery.
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Thromboprophylaxis and laboratory monitoring for in-hospital patients with COVID-19 - a Swiss consensus statement by the Working Party Hemostasis.
Alessandro Casini,Lorenzo Alberio,Anne Angelillo-Scherrer,Pierre Fontana,Bernhard Gerber,Lukas Graf,Inga Hegemann,Wolfgang Korte,Johanna A. Kremer Hovinga,Thomas Pierre Lecompte,Maria Martinez,Michael Nagler,Jan-Dirk Studt,Dimitrios A. Tsakiris,Walter A. Wuillemin,Lars M. Asmis +15 more
Suggestions for thromboprophylaxis and laboratory monitoring for in-hospital patients with COVID-19 - a Swiss consensus statement by the Working Party Hemostasis.
Alessandro Casini,Lorenzo Alberio,Anne Angelillo-Scherrer,Pierre Fontana,Bernhard Gerber,Lukas Graf,Inga Hegemann,Wolfgang Korte,Johanna A. Kremer Hovinga,Thomas Lecompte,Maria Martinez,Michael Nagler,Jan-Dirk Studt,Dimitrios A. Tsakiris,Walter A. Wuillemin,Lars M. Asmis +15 more
TL;DR: Recommendations for pharmacological thromboprophylaxis in COVID-19 patients in the acute setting and recommendations from international societies are presented.
Journal ArticleDOI
Fitusiran, an Investigational RNAi Therapeutic Targeting Antithrombin for the Treatment of Hemophilia: Updated Results from a Phase 1 and Phase 1/2 Extension Study in Patients without Inhibitors
Margaret V. Ragni,Pencho Georgiev,Tim Mant,Michael Desmond Creagh,Toshko Lissitchkov,David H. Bevan,Steve Austin,Charles R. M. Hay,Inga Hegemann,Rashid S. Kazmi,Pratima Chowdary,Savita Rangarajan,Chang-Heok Soh,Akin Akinc,Angela M. Partisano,Benny Sorenson,K. John Pasi +16 more
TL;DR: The updated safety, pharmacodynamic (PD) effect, and clinical activity of fitusiran in patients with hemophilia with inhibitors as well as long term data from the Phase 1/2 extension study are reported.