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Inga Wessels
Researcher at RWTH Aachen University
Publications - 33
Citations - 1502
Inga Wessels is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Zinc deficiency. The author has an hindex of 12, co-authored 23 publications receiving 881 citations.
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Journal ArticleDOI
Zinc as a Gatekeeper of Immune Function
TL;DR: Molecular mechanisms underlying the development of a pro-inflammatory phenotype during zinc deficiency are reported, and links between altered zinc homeostasis and disease development are described, ensuring the benefits of zinc supplementation for a malfunctioning immune system become clear.
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The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis.
TL;DR: The potential of zinc as preventive and therapeutic agent alone or in combination with other strategies, as zinc meets all the above described criteria is discussed.
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Zinc Signals and Immunity.
TL;DR: The role of zinc in regulating intracellular signaling pathways in innate as well as adaptive immune cells, including kinases, caspases, phosphatases, and phosphodiesterases, will be highlighted in this article.
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Zinc deficiency induces production of the proinflammatory cytokines IL-1β and TNFα in promyeloid cells via epigenetic and redox-dependent mechanisms
TL;DR: Mechanisms explaining the increase in proinflammatory cytokine production during zinc deficiency are defined, focusing on the role of epigenetic and redox-mediated mechanisms.
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Immunosenescence of polymorphonuclear neutrophils.
TL;DR: This work has shown that in addition to their traditional role as phagocytes, neutrophils are able to secrete a wide array of immunomodulating molecules, and the finding that genetic defects that lead to neutropenia increase susceptibility to infections is underlined.