Ingmar Glauche

TL;DR: This work shows for two independent datasets that clinically observed BCR-ABL1 transcript dynamics during imatinib treatment of CML can consistently be explained by a selective functional effect ofImatinib on proliferative leukemia stem cells, and suggests the general potential of imatin ib to induce a complete elimination of the malignant clone.

TL;DR: A simple quantitative model describing the interaction of two transcription factors is proposed and it is demonstrated the ability of the model to account for the observed switching behavior of a transition from a state of low expression of both factors (undifferentiated state) to the dominance of one factor (differentiated state).

TL;DR: In this article, a simple quantitative model describing the interaction of two transcription factors was proposed to account for the observed switching behavior of a transition from a state of low expression of both factors (undifferentiated state) to the dominance of one factor (differentiated state).

TL;DR: In this article, a simple distributed protocol for wireless multi-hop ad-hoc networks is proposed, guaranteeing strong connectivity almost surely and independently of various typical uncorrelated and correlated random spatial patterns of participating ad hoc nodes.

TL;DR: This work presents fluorescently tagged endogenous proliferating cell nuclear antigen (PCNA) as an all-in-one cell cycle reporter that allows simultaneous analysis of cell cycle progression, including the transition into quiescence, and the dynamics of individual fate determinants.