Iqbal Unnisa Ali

TL;DR: The mutational spectra of the PTEN/MMAC1 gene in tumors from various tissues, especially endometrium, brain, prostate, and ovary, are reviewed, suggesting that depending on the tissue type, the gene appears to be involved in the initiation or the progression of cancers.

TL;DR: A significant role for VEGPF is suggested in the development of CNS tumor neovascularity and peritumoral edema and in capillary hemangioblastomas.

TL;DR: Because of their safety and the fact that they are not perceived as "medicine," food-derived products are highly interesting for development as chemopreventive agents that may find widespread, long-term use in populations at normal risk.

TL;DR: Analysis of genomic organization and expression of platelet-derived growth factor receptors (PDGFR) and epidermal growth factor receptor (EGFR) in human malignant gliomas showed amplification and overexpression of both receptors in distinct subsets of tumors.

TL;DR: The results presented here demonstrate a loss of heterozygosity of several genes on chromosome 11 in primary breast tumors, and restriction fragment length polymorphism analysis of these DNAs suggests that the most frequent loss of sequences in breast tumors occurs between the beta-globin and parathyroid hormone loci on the short arm of chromosome 11.