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Irene Scalera
Researcher at University Hospitals Birmingham NHS Foundation Trust
Publications - 23
Citations - 865
Irene Scalera is an academic researcher from University Hospitals Birmingham NHS Foundation Trust. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 10, co-authored 18 publications receiving 617 citations. Previous affiliations of Irene Scalera include Queen Elizabeth Hospital Birmingham & Sapienza University of Rome.
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Journal ArticleDOI
First Comparison of Hypothermic Oxygenated PErfusion Versus Static Cold Storage of Human Donation After Cardiac Death Liver Transplants: An International-matched Case Analysis.
Philipp Dutkowski,Wojciech G. Polak,Paolo Muiesan,Andrea Schlegel,Cornelia J. Verhoeven,Irene Scalera,Michelle L. DeOliveira,Philipp Kron,Pierre-Alain Clavien +8 more
TL;DR: No graft failure due to intrahepatic cholangiopathy or nonfunction occurred in HOPE-treated livers, whereas 18% of unperfused DCD livers needed retransplantation.
Journal ArticleDOI
The UK DCD Risk Score: A new proposal to define futility in donation-after-circulatory-death liver transplantation.
Andrea Schlegel,Marit Kalisvaart,Irene Scalera,Richard W. Laing,Hynek Mergental,Darius F. Mirza,Thamara Perera,John Isaac,Philipp Dutkowski,Paolo Muiesan +9 more
TL;DR: The UK DCD Risk Score is a reliable tool to detect high-risk and futile combinations of donor-and-recipient factors in DCD liver transplantation and offers a great potential for making better decisions on which DCD graft should be rejected or may benefit from functional assessment and further optimization by machine perfusion.
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Liver Transplantation Using Grafts From Donors After Circulatory Death: A Propensity Score-Matched Study From a Single Center.
Richard W. Laing,Irene Scalera,John Isaac,John Isaac,Hynek Mergental,Darius F. Mirza,Darius F. Mirza,James Hodson,R. J. W. Wilkin,M. T. P. R. Perera,M. T. P. R. Perera,Paolo Muiesan,Paolo Muiesan +12 more
TL;DR: With appropriate recipient selection, the use of DCDs, including those deemed marginal, can be safe and can produce outcomes comparable to those seen using DBD grafts in similar recipients.
Journal ArticleDOI
Impact of donor age in donation after circulatory death liver transplantation: Is the cutoff "60" still of relevance?
Andrea Schlegel,Irene Scalera,M. Thamara P. R. Perera,M. Thamara P. R. Perera,Marit Kalisvaart,Hynek Mergental,Darius F. Mirza,Darius F. Mirza,John Isaac,Paolo Muiesan +9 more
TL;DR: Older DCD donors can be successfully used for liver transplantation with good longterm outcomes when further risk factors are limited, and donor body mass index above a threshold of 25 kg/m2 significantly impacted on graft and patient survival at any donor age, whereas donor warm ischemia times were not predictive for graft loss.
Journal ArticleDOI
Acute kidney injury and post-reperfusion syndrome in liver transplantation.
Ilaria Umbro,Francesca Tinti,Irene Scalera,Felicity Evison,Bridget Gunson,Adnan Sharif,James Ferguson,Paolo Muiesan,Anna Paola Mitterhofer +8 more
TL;DR: It is aimed to consider all the relevant aspects involved in PRS-induced AKI in the setting of LT and to identify all studies that better clarified the specific mechanisms linking PRS and AKI, avoiding confounding factors.