I
Irina G. Gazaryan
Researcher at Moscow State University
Publications - 124
Citations - 4286
Irina G. Gazaryan is an academic researcher from Moscow State University. The author has contributed to research in topics: Horseradish peroxidase & Peroxidase. The author has an hindex of 32, co-authored 120 publications receiving 3910 citations. Previous affiliations of Irina G. Gazaryan include Cornell University & Ohio State University.
Papers
More filters
Journal ArticleDOI
Direct electron transfer between heme-containing enzymes and electrodes as basis for third generation biosensors
Lo Gorton,Annika Lindgren,Ted Larsson,Florentina-Daniela Munteanu,Tautgirdas Ruzgas,Irina G. Gazaryan +5 more
TL;DR: In this article, direct electron transfer between redox enzymes and electrodes found the basis for third generation biosensors, which were used for bioelectrochemistry of redox enzyme and electrodes.
Journal ArticleDOI
Comparison of physico-chemical characteristics of four laccases from different basidiomycetes.
Sergey Shleev,Olga Morozova,O. V. Nikitina,E. S. Gorshina,T. V. Rusinova,Vladimir A. Serezhenkov,Dosymzhan Sh. Burbaev,Irina G. Gazaryan,Alexander I. Yaropolov +8 more
TL;DR: It could be concluded that T. hirsuta and Cerrena maxima laccases have some superior characteristics such as high stability, high activity, and low carbohydrate content, making them attractive objects for further investigations as well as for application in different areas of biotechnology.
Journal ArticleDOI
Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms
Thomas W. Faust,Eric H. Chang,Czeslawa Kowal,RoseAnn Berlin,Irina G. Gazaryan,Eva Bertini,Jie Zhang,Jorge Sanchez-Guerrero,Hilda Fragoso-Loyo,Bruce T. Volpe,Betty Diamond,Patricio T. Huerta +11 more
TL;DR: The mechanisms by which NMDAR-reactive AAbs trigger graded cellular alterations are revealed, which are likely to be responsible for the transient and permanent neuropsychiatric symptoms observed in patients with SLE.
Journal ArticleDOI
Zinc Is a Potent Inhibitor of Thiol Oxidoreductase Activity and Stimulates Reactive Oxygen Species Production by Lipoamide Dehydrogenase
Irina G. Gazaryan,Boris F. Krasnikov,Gillian A. Ashby,Roger N. F. Thorneley,Bruce S. Kristal,Abraham M. Brown +5 more
TL;DR: The results suggest that Zn2+ can interfere with mitochondrial antioxidant production and may also stimulate production of reactive oxygen species by a novel mechanism.
Journal ArticleDOI
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease
Manuj Ahuja,Navneet Ammal Kaidery,Lichuan Yang,Noel Y. Calingasan,N. A. Smirnova,Arsen Gaisin,Irina N. Gaisina,Irina G. Gazaryan,Dmitry M. Hushpulian,Ismail Kaddour-Djebbar,Wendy B. Bollag,John C. Morgan,Rajiv R. Ratan,Anatoly A. Starkov,M. Flint Beal,Bobby Thomas +15 more
TL;DR: Preclinical evidence is provided that a Food and Drug Administration-approved drug, dimethylfumarate (DMF), and its metabolite monomethylfumarry (MMF) can block nigrostriatal dopaminergic neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of PD.