Isabel Vitória Figueiredo

TL;DR: Extracted insulin from microspheres decreased hyperglycemia of diabetic rats proving to be bioactive and showing that encapsulation in alginatemicrospheres using the emulsification/internal gelation is an appropriate method for protein encapsulation.

TL;DR: The most important aspects to take into account when performing the maximal electroshock seizure (MES) test in the routine laboratory screening of new antiepileptics: the conventional and threshold MES test experimental procedures, the factors affecting experimental data and the assessment of anticonvulsant activity are discussed.

TL;DR: These findings showed the different roles of pharmacists during the COVID-19 pandemic, such as disease prevention and infection control, adequate storage and drug supply, patient care and support for healthcare professionals.

TL;DR: The nanoformulation facilitated the oral delivery of insulin, and potentially that of other therapeutic proteins, through chemical and physical facilitation of permeation through the intestinal membrane.

TL;DR: The developed nanoparticles may be applied as topical treatment, after encapsulation of betamethasone-21-acetate, as nanoparticles promote prolonged drug release, increase drug stability in aqueous media, reducing drug degradation, and increase drug permeability through lipid membranes.