Isabelle Aujard

TL;DR: The o-nitrobenzyl platform for designing photolabile protecting groups with red-shifted absorption that could be photolyzed upon one- and two-photon excitation is evaluated and the difficulty in enlarging the corresponding action uncaging cross-sections is emphasized in view of the observed trend of their quantum yield of uncaging.

TL;DR: Gold nanoparticles as well as planar gold surfaces can be efficiently grafted with a covalently attached polymer monolayer a few nanometers thick, by simple contact of the metal surface with dilute aqueous solutions of hydrophilic polymers that are end-capped with disulfide moieties, as shown by UV/vis absorption, dynamic light scattering, and surface plasmon resonance studies.

TL;DR: The small and synthetically easily accessible coumarinylmethyl backbone has been modified to generate a family of photolabile protecting groups with redshifted absorption that is relevant for uncaging with cyan light and favorable to perform chromatic orthogonal photoactivation with UV and blue-cyan light sources.

TL;DR: The small and synthetically easily accessible 7-diethylamino-4-thiocoumarinylmethyl photolabile protecting group has been validated for uncaging with blue light.

TL;DR: The careful kinetic analysis allows us to discuss the relevance of the o-hydroxycinnamic platform for diverse caging applications with one- and two-photon excitation and satisfactorily compare with the most efficient caging groups reported to date.