I
Isabelle Caillé
Researcher at University of Paris
Publications - 19
Citations - 6089
Isabelle Caillé is an academic researcher from University of Paris. The author has contributed to research in topics: Olfactory bulb & Neurogenesis. The author has an hindex of 12, co-authored 17 publications receiving 5863 citations. Previous affiliations of Isabelle Caillé include Centre national de la recherche scientifique & Rockefeller University.
Papers
More filters
Journal ArticleDOI
Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain
Fiona Doetsch,Isabelle Caillé,Daniel A. Lim,José Manuel García-Verdugo,Arturo Alvarez-Buylla +4 more
TL;DR: It is shown that SVZ astrocytes act as neural stem cells in both the normal and regenerating brain and give rise to cells that grow into multipotent neurospheres in vitro.
Journal ArticleDOI
EGF Converts Transit-Amplifying Neurogenic Precursors in the Adult Brain into Multipotent Stem Cells
Fiona Doetsch,Leopoldo Petreanu,Isabelle Caillé,José Manuel García-Verdugo,Arturo Alvarez-Buylla,Arturo Alvarez-Buylla +5 more
TL;DR: It is shown that transit-amplifying C cells retain stem cell competence under the influence of growth factors and are 53-fold enriched for neurosphere generation.
Journal ArticleDOI
Multipotent Neural Stem Cells Reside into the Rostral Extension and Olfactory Bulb of Adult Rodents
Angela Gritti,Luca Bonfanti,Fiona Doetsch,Isabelle Caillé,Arturo Alvarez-Buylla,Daniel A. Lim,Rossella Galli,José Manuel García Verdugo,Daniel G. Herrera,Angelo L. Vescovi +9 more
TL;DR: It is demonstrated that stem cells are not confined to the forebrain periventricular region and indicate that stem Cells endowed with different functional characteristics occur at different levels of the SVZ–RE pathway.
Journal ArticleDOI
Lack of the Cell-Cycle Inhibitor p27Kip1 Results in Selective Increase of Transit-Amplifying Cells for Adult Neurogenesis
Fiona Doetsch,Fiona Doetsch,José Manuel García Verdugo,Isabelle Caillé,Arturo Alvarez-Buylla,Moses V. Chao,Patrizia Casaccia-Bonnefil +6 more
TL;DR: It is shown that loss of the cyclin-dependent kinase inhibitor p27Kip1 has very specific effects on a population of CNS progenitors responsible for adult neurogenesis, and cell-cycle regulation of SVZ adult progenitor is remarkably cell-type specific, with p27 Kip1 being a key regulator of the cell division of the transit-amplifying progenites.
Journal ArticleDOI
Internalization of D1 dopamine receptor in striatal neurons in vivo as evidence of activation by dopamine agonists.
TL;DR: The results demonstrate that, in vivo, the acute activation of dopamine receptors by direct agonists or endogenously released dopamine provokes dramatic modifications of their subcellular distribution in neurons, including internalization in the endosomal compartment in the cytoplasm.