M
Moses V. Chao
Researcher at New York University
Publications - 323
Citations - 42254
Moses V. Chao is an academic researcher from New York University. The author has contributed to research in topics: Neurotrophin & Receptor. The author has an hindex of 108, co-authored 314 publications receiving 39827 citations. Previous affiliations of Moses V. Chao include Columbia University & Cornell University.
Papers
More filters
Journal ArticleDOI
Neurotrophins and their receptors: a convergence point for many signalling pathways.
TL;DR: Recent findings that neurotrophins, in addition to promoting survival and differentiation, exert various effects through surprising interactions with other receptors and ion channels are reviewed.
Journal ArticleDOI
The trk proto-oncogene product: a signal transducing receptor for nerve growth factor
TL;DR: Affinity cross-linking and equilibrium binding experiments with 125I-labeled NGF indicate that p140prototrk binds NGF specifically in cultured cells with a dissociation constant of 10(-9) molar.
Journal ArticleDOI
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.
Huai-hu Chuang,Elizabeth D. Prescott,Haeyoung Kong,Shannon D. Shields,Sven-Eric Jordt,Allan I. Basbaum,Moses V. Chao,David Julius +7 more
TL;DR: It is shown that bradykinin- or NGF-mediated potentiation of thermal sensitivity in vivo requires expression of VR1, a heat-activated ion channel on sensory neurons, and biochemical studies suggest that VR1 associates with this complex.
Journal ArticleDOI
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor.
TL;DR: Reconstitution experiments reveal a new growth factor receptor-mediated mechanism of cellular differentiation involving trk and the low-affinity NGF receptor and the tyrosine kinase trk gene product.
Journal ArticleDOI
TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells*
Brian Wong,Jaerang Rho,Joseph R. Arron,Elizabeth Robinson,Jason R. Orlinick,Moses V. Chao,Sergey Kalachikov,Eftihia Cayani,Frederick S. Bartlett,Wayne N. Frankel,Soo Young Lee,Yongwon Choi +11 more
TL;DR: A role for this TNF-related ligand in the regulation of the T cell-dependent immune response is suggested.