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Isabelle Fleury
Researcher at Université de Montréal
Publications - 51
Citations - 2971
Isabelle Fleury is an academic researcher from Université de Montréal. The author has contributed to research in topics: Diffuse large B-cell lymphoma & Medicine. The author has an hindex of 14, co-authored 38 publications receiving 1722 citations. Previous affiliations of Isabelle Fleury include Paris Diderot University & Hôpital Maisonneuve-Rosemont.
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Journal ArticleDOI
Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Stephen J. Schuster,Michael R. Bishop,Constantine S. Tam,Edmund K. Waller,Peter Borchmann,Joseph P. McGuirk,Ulrich Jäger,Samantha Jaglowski,Charalambos Andreadis,Jason R. Westin,Isabelle Fleury,Veronika Bachanova,S. Ronan Foley,P. Joy Ho,Stephan Mielke,Stephan Mielke,John M. Magenau,Harald Holte,Serafino Pantano,Lida Bubuteishvili Pacaud,Rakesh Awasthi,Jufen Chu,Özlem Anak,Gilles Salles,Richard T. Maziarz +24 more
TL;DR: The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas in a single-center, phase 2a study.
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Long-term clinical outcomes of tisagenlecleucel in patients with relapsed or refractory aggressive B-cell lymphomas (JULIET): a multicentre, open-label, single-arm, phase 2 study.
Stephen J. Schuster,Constantine S. Tam,Peter Borchmann,Nina Worel,Joseph P. McGuirk,Harald Holte,Edmund K. Waller,Samantha Jaglowski,Michael R. Bishop,Lloyd E. Damon,Stephen Ronan Foley,Jason R. Westin,Isabelle Fleury,P. Joy Ho,Stephan Mielke,Stephan Mielke,Takanori Teshima,Murali Janakiram,Jingmei Hsu,Koji Izutsu,Marie José Kersten,Monalisa Ghosh,Nina D. Wagner-Johnston,Koji Kato,Paolo Corradini,Marcela Martinez-Prieto,Xia Han,Ranjan Tiwari,Gilles Salles,Richard T. Maziarz +29 more
TL;DR: Tisagenlecleucel showed durable activity and manageable safety profiles in adult patients with relapsed or refractory aggressive B-cell lymphomas in the pivotal JULIET trial.
Journal ArticleDOI
Primary Analysis of Juliet: A Global, Pivotal, Phase 2 Trial of CTL019 in Adult Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Stephen J. Schuster,Michael R. Bishop,Constantine S. Tam,Edmund K. Waller,Peter Borchmann,Joseph P. McGuirk,Ulrich Jaeger,Samantha Jaglowski,Charalambos Andreadis,Jason R. Westin,Isabelle Fleury,Veronika Bachanova,Stephen Ronan Foley,P. Joy Ho,Stephan Mielke,John M. Magenau,Harald Holte,Koen van Besien,Marie José Kersten,Takanori Teshima,Kensei Tobinai,Paolo Corradini,Oezlem Anak,Lida Bubuteishvili Pacaud,Christopher del Corral,Rakesh Awasthi,Feng Tai,Gilles Salles,Richard T. Maziarz +28 more
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Retrospective study of intravascular large B-cell lymphoma cases diagnosed in Quebec: A retrospective study of 29 case reports.
Vanessa Brunet,Sofia Marouan,Jean-Pierre Routy,Mohamed Amin Hashem,Vincent Bernier,Raynald Simard,T. Petrella,Louis Lamarre,Gilles Théorêt,Christian Carrier,Hans Knecht,Isabelle Fleury,Michel Pavic +12 more
TL;DR: The study showed that the French Canadian presentation of this subtype of IVL is more frequently observed with neurological rather than cutaneous involvement, and an early diagnosis is of primary importance since almost a quarter of patients receive a post-mortem diagnosis.
Journal ArticleDOI
Tisagenlecleucel in relapsed/refractory diffuse large B-cell lymphoma patients without measurable disease at infusion
Michael R. Bishop,Richard T. Maziarz,Edmund K. Waller,Ulrich Jäger,Jason R. Westin,Joseph P. McGuirk,Isabelle Fleury,Harald Holte,Peter Borchmann,Christopher del Corral,Ranjan Tiwari,Özlem Anak,Rakesh Awasthi,Lida Bubuteishvili Pacaud,Vadim V. Romanov,Stephen J. Schuster +15 more
TL;DR: Preliminary evidence of tisagenlecleucel efficacy in patients with r/r DLBCL without detectable disease after bridging or salvage therapies is provided and warrant further investigation of the drug as consolidative therapy in future trials.