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Isao Sanada
Researcher at Kumamoto University
Publications - 33
Citations - 831
Isao Sanada is an academic researcher from Kumamoto University. The author has contributed to research in topics: Leukemia & T-cell leukemia. The author has an hindex of 12, co-authored 33 publications receiving 816 citations.
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Journal Article
Chromosome Abnormalities in Adult T-Cell Leukemia/Lymphoma: A Karyotype Review Committee Report
Nanao Kamada,Masaharu Sakurai,Kanji Miyamoto,Isao Sanada,Naoki Sadamori,Shirou Fukuhara,Syuiti Abe,Yukimasa Shiraishi,Tatsuo Abe,Yasuhiko Kaneko,Masanori Shimoyama +10 more
TL;DR: The combination of rearrangement in 14q32 and monosomy X and that of trisomy 3 and deletion in 6q21 occurred only in the acute or lymphoma type and may be associated with the aggressiveness in adult T-cell leukemia/lymphoma.
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Plasma cell dyscrasia with polyneuropathy and endocrine disorder: Clinical and laboratory features of 109 reported cases
Kiyoshi Takatsuki,Isao Sanada +1 more
TL;DR: Surgical excision or irradiation of the local lesion and administration of corticosteroids and/or anti-cancer drugs are effective in improving polyneuropathy and other systemic symptoms.
Journal Article
Clinical diversity in adult T-cell leukemia-lymphoma.
Kiyoshi Takatsuki,Kazunari Yamaguchi,Fumio Kawano,Toshio Hattori,Hiromichi Nishimura,Hiroyuki Tsuda,Isao Sanada,Kiyonobu Nakada,Yayeko Itai +8 more
TL;DR: Variations in the clinical features of atypical cases suggest a division of the spectrum of ATL into five types: acute, chronic, smoldering, crisis, and lymphoma, and family studies showed that the routes of natural infection of HTLV-I are from mother to child and also from husband to wife.
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Polyclonal integration of HTLV-I proviral DNA in lymphocytes from HTLV-I seropositive individuals : An intermediate state between the healthy carrier state and smouldering ATL
Kazunari Yamaguchi,Kazunari Yamaguchi,Tetsuyuki Kiyokawa,Kiyonobu Nakada,Lee Song Yul,Norio Asou,Toshinori Ishii,Isao Sanada,Motoharu Seiki,Mitsuaki Yoshida,E. Matutes,D. Catovsky,Kiyoshi Takatsuki +12 more
TL;DR: The only haematological abnormality in these patients was the presence of few atypical lymphoid cells in the peripheral blood.
Journal ArticleDOI
Chromosomal aberrations in adult T cell leukemia: relationship to the clinical severity
Isao Sanada,Ryuji Tanaka,Etsuko Kumagai,Hiroyuki Tsuda,Hiromichi Nishimura,Kazunari Yamaguchi,Fumio Kawano,Hirokazu Fujiwara,Kiyoshi Takatsuki +8 more
TL;DR: The present findings indicate that the more aggressive the clinical course of ATL, the more complex the numerical and structural chromosome abnormality.