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Istvan Ladunga
Researcher at University of Nebraska–Lincoln
Publications - 36
Citations - 3051
Istvan Ladunga is an academic researcher from University of Nebraska–Lincoln. The author has contributed to research in topics: Gene & Peak calling. The author has an hindex of 22, co-authored 36 publications receiving 2804 citations. Previous affiliations of Istvan Ladunga include Baylor College of Medicine & Hungarian Academy of Sciences.
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PANTHER: A browsable database of gene products organized by biological function, using curated protein family and subfamily classification
Paul Thomas,Anish Kejariwal,Michael J. Campbell,Huaiyu Mi,Karen Diemer,Nan Guo,Istvan Ladunga,Betty Ulitsky-Lazareva,Anushya Muruganujan,Steven Rabkin,Jody Vandergriff,Olivier Doremieux +11 more
TL;DR: The PANTHER database was designed for high-throughput analysis of protein sequences, which allows browsing of the database by biological functions and includes training sequences from all organisms in the GenBank non-redundant protein database.
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Practical Guidelines for the Comprehensive Analysis of ChIP-seq Data
Timonthy Bailey,Paweł Krajewski,Istvan Ladunga,Celine Lefebvre,Qiang Li,Tao Liu,Pedro Madrigal,Cenny Taslim,Jie Zhang +8 more
TL;DR: All the major steps in the analysis of ChIP-seq data: sequencing depth selection, quality checking, mapping, data normalization, assessment of reproducibility, peak calling, differential binding analysis, controlling the false discovery rate, peak annotation, visualization, and motif analysis are addressed.
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The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation
Guillaume Blanc,Irina Agarkova,Jane Grimwood,Alan Kuo,Andrew J. Brueggeman,David D. Dunigan,James R. Gurnon,Istvan Ladunga,Erika Lindquist,Susan Lucas,Jasmyn Pangilinan,Thomas Pröschold,Asaf Salamov,Jeremy Schmutz,Donald P. Weeks,Takashi Yamada,Alexandre Lomsadze,Mark Borodovsky,Jean-Michel Claverie,Igor V. Grigoriev,James L. Van Etten +20 more
TL;DR: Comparison of these genomic features with the adaptive strategies of psychrophilic microbes suggests that prokaryotes and eukaryotes followed comparable evolutionary routes to adapt to cold environments.
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Transcriptome-Wide Changes in Chlamydomonas reinhardtii Gene Expression Regulated by Carbon Dioxide and the CO2-Concentrating Mechanism Regulator CIA5/CCM1
Wei Fang,Yaqing Si,Stephen Douglass,David Casero,Sabeeha S. Merchant,Matteo Pellegrini,Istvan Ladunga,Peng Liu,Martin H. Spalding +8 more
TL;DR: An impact of CO2 and CIA5, a key transcription regulator, on expression of almost 25% of all Chlamydomonas genes is observed, and an array of gene clusters with distinctive expression patterns that provide insight into the regulatory interaction between CIA5 and CO2 are discovered.
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Dynamic changes in genome-wide histone H3 lysine 4 methylation patterns in response to dehydration stress in Arabidopsis thaliana
Karin V. van Dijk,Karin V. van Dijk,Yong Ding,Sridar Achary Malkaram,Jean-Jack M Riethoven,Rong Liu,Rong Liu,Jingyi Yang,Jingyi Yang,Peter Laczko,Han Chen,Yuannan Xia,Istvan Ladunga,Zoya Avramova,Michael E. Fromm +14 more
TL;DR: The broad H3K4me3 distribution profiles on nucleosomes of stress-induced genes uncovered a specific chromatin pattern associated with many of the genes involved in the dehydration stress response.