Ivan Rios-Mondragon

TL;DR: The first comprehensive overview of the microfluidic systems used as innovative tools in the studies of lung cancer metastasis including single cancer cell analysis, endothelial transmigration, distant niches migration and finally neoangiogenesis is presented.

TL;DR: An overview of ongoing clinical trials focusing on combination therapies employing epi-drugs for breast cancer treatment is provided and the latest nano-based targeted delivery approaches forEpigenome modulation are summarized, highlighting the current limitations and obstacles associated with applying these experimental strategies in the clinics.

TL;DR: It is reported that THSer(P)-31 co-distributes with the Golgi complex and synaptic-like vesicles in rat and human dopaminergic cells and indicates that Ser-31 phosphorylation may regulate TH subcellular localization by enabling its transport along microtubules, notably toward the projection terminals.

TL;DR: In this paper , the authors investigated the ability of DNA methyltransferase (DNMT) inhibitor decitabine (DAC) to increase the sensitivity of breast cancer cells to anthracycline antibiotic doxorubicin (DOX).

TL;DR: The authors' data indicates that cellular protrusions and tubular recycling endosomes are important for codeIT, and an siRNA-based screening using this method revealed the involvement of several myosins and small GTPases as codeIT regulators.