I
Iwona Brzozowska
Researcher at Jagiellonian University Medical College
Publications - 27
Citations - 1081
Iwona Brzozowska is an academic researcher from Jagiellonian University Medical College. The author has contributed to research in topics: Melatonin & Gastric mucosa. The author has an hindex of 14, co-authored 27 publications receiving 1015 citations. Previous affiliations of Iwona Brzozowska include Jagiellonian University.
Papers
More filters
Journal Article
Role of prostaglandins in gastroprotection and gastric adaptation.
TL;DR: Gastric adaptation appears to be long-lasting phenomenon accompanied by increased resistance of the adapted mucosa to subsequent damage induced by corrosive agents, unlike short lived gastroprotection by PG, NO, CGRP, mild irritants or short ischemia.
Journal Article
Localization and biological activities of melatonin in intact and diseased gastrointestinal tract (GIT).
Stanislaw J. Konturek,P C Konturek,Iwona Brzozowska,Michal Pawlik,Zbigniew Sliwowski,M Cześnikiewicz-Guzik,Slawomir Kwiecien,T. Brzozowski,G A Bubenik,Wieslaw W. Pawlik +9 more
TL;DR: This review focuses on the localization, production, metabolism and the functions of MT in GIT and the duodenal unit (liver, biliary routes and pancreas), where multi-step biosynthetic pathways of this indole, similar to those in pinealocytes, have been identified.
Journal ArticleDOI
The role of melatonin and L‐tryptophan in prevention of acute gastric lesions induced by stress, ethanol, ischemia, and aspirin
Tomasz Brzozowski,P C Konturek,Stanislaw J. Konturek,Robert Pajdo,Wladyslaw Bielanski,Iwona Brzozowska,Jerzy Stachura,Eckhart G. Hahn +7 more
TL;DR: The role of melatonin and L‐tryptophan in prevention of acute gastric lesions induced by stress, ethanol, ischemia, and aspirin is studied.
Journal ArticleDOI
Role of leptin in ulcer healing
Peter C. Konturek,Tomasz Brzozowski,Zora Sulekova,Iwona Brzozowska,Aleksandra Duda,Holger Meixner,Eckhart G. Hahn,Stanislaw J. Konturek +7 more
TL;DR: It is concluded that leptin accelerates ulcer healing by mechanisms involving the up- regulation of TGFalpha and increased production of nitric oxide due to up-regulation of cNOS and iNOS in the ulcer area.
Journal ArticleDOI
Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan.
Iwona Brzozowska,Peter C. Konturek,Tomasz Brzozowski,Stanislaw J. Konturek,Slawomir Kwiecien,Robert Pajdo,Danuta Drozdowicz,Michal Pawlik,Agata Ptak,Eckhart G. Hahn +9 more
TL;DR: The effects of intragastric administration of melatonin and its precursor, L‐tryptophan, with or without concurrent treatment with luzindole, a selective antagonist ofmelatonin MT2 receptors, on healing of chronic gastric ulcers induced by serosal application of acetic acid are compared.