J Bas

TL;DR: The presence of an IgA linear pattern on the kidney biopsy specimen and circulating anti-glomerular basement membrane (GBM) IgA antibodies led to the diagnosis of Goodpasture syndrome, which implies the possibility that the well-known pulmonary involvement during the course of Schönlein-Henoch purpura could be caused by Good Pasture syndrome in certain cases.

TL;DR: In this article, the involvement of the immune system in Parkinson's disease was assessed using the phenotype of circulating lymphocytes in 30 untreated and 34 treated patients, and they found a numeric decrease in helper T cells (higher in CD4+CD45RA(+) than in CD+CD29(+)) and B cells, and a rise in activated, CD4(+)CD25(+) lymphocytes that was correlated with lymphocyte depletion.

TL;DR: Reaching donor-specific hyporesponsiveness is feasible after renal transplantation and associated with Treg recruitment in the graft, suggesting that the recruitment of Tregs in the allograft plays an important role for renal acceptance.

TL;DR: Standard Ficoll-Paque separation and cryopreservation of mononuclear cells alter the measurement of lymphocyte subsets by flow cytometry, which increased the percentage of CD4+, CD19+ and CD4+CD45RA+ cells, as well as decreasing that of CD8+, and CD3+CD29+ cells compared to the fresh whole blood lysis technique.

TL;DR: In renal transplantation, chronic allograft nephropathy is the leading cause of long-term graft losses, transplant glomerulopathy being its glomerular form, and hepatitis C virus infection may be associated with type II cryoglobulinemia which may lead to membranoproliferativeglomerulonephritis.