Mariona Mestre

TL;DR: The presence of an IgA linear pattern on the kidney biopsy specimen and circulating anti-glomerular basement membrane (GBM) IgA antibodies led to the diagnosis of Goodpasture syndrome, which implies the possibility that the well-known pulmonary involvement during the course of Schönlein-Henoch purpura could be caused by Good Pasture syndrome in certain cases.

TL;DR: In this article, the involvement of the immune system in Parkinson's disease was assessed using the phenotype of circulating lymphocytes in 30 untreated and 34 treated patients, and they found a numeric decrease in helper T cells (higher in CD4+CD45RA(+) than in CD+CD29(+)) and B cells, and a rise in activated, CD4(+)CD25(+) lymphocytes that was correlated with lymphocyte depletion.

TL;DR: Reaching donor-specific hyporesponsiveness is feasible after renal transplantation and associated with Treg recruitment in the graft, suggesting that the recruitment of Tregs in the allograft plays an important role for renal acceptance.

TL;DR: In Parkinson patients, peripheral blood CD4(+) T cells have an increased susceptibility to apoptosis with Fas involvement, which explains the decrease in the number of CD4 (+) T-cell subsets observed in Parkinson and could be related to the neurodegenerative process.

TL;DR: Results indicate that the concomitant association of CsA and ALG or OKT3 constitutes a safe and effective therapeutic strategy that provides a low incidence of rejection and gives good results for patient and graft survival.