J
J. Christopher Edgar
Researcher at Children's Hospital of Philadelphia
Publications - 112
Citations - 4862
J. Christopher Edgar is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Magnetoencephalography & Auditory cortex. The author has an hindex of 36, co-authored 102 publications receiving 4159 citations. Previous affiliations of J. Christopher Edgar include University of Illinois at Urbana–Champaign & University of Pennsylvania.
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Journal ArticleDOI
Comparison of different cortical connectivity estimators for high-resolution EEG recordings.
Laura Astolfi,Febo Cincotti,Donatella Mattia,M. Grazia Marciani,Luiz A. Baccalá,Fabrizio De Vico Fallani,Serenella Salinari,Mauro Ursino,Melissa Zavaglia,Lei Ding,J. Christopher Edgar,Gregory A. Miller,Bin He,Fabio Babiloni +13 more
TL;DR: Functional connectivity patterns of cortical activity can be effectively estimated under general conditions met in most EEG recordings by combining high‐resolution EEG techniques, linear inverse estimation of the cortical activity, and frequency domain multivariate methods such as PDC, DTF, and dDTF.
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Validating γ oscillations and delayed auditory responses as translational biomarkers of autism.
Michael J. Gandal,J. Christopher Edgar,Richard S. Ehrlichman,Mili Mehta,Timothy P.L. Roberts,Steven J. Siegel +5 more
TL;DR: A novel preclinical approach toward mechanistic understanding and treatment development for autism is demonstrated, with selective behavioral alterations related to autism demonstrated in VPA-exposed mice.
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Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia.
Michael J. Gandal,J. Christopher Edgar,Kerstin Klook,Kerstin Klook,Kerstin Klook,Steven J. Siegel +5 more
TL;DR: It is proposed that analogous signal-to-noise deficits in the flow of cortical information in preclinical models are useful targets for the development of new drugs that target the treatment-resistant symptoms of schizophrenia.
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MEG detection of delayed auditory evoked responses in autism spectrum disorders: towards an imaging biomarker for autism.
Timothy P.L. Roberts,Sarah Y. Khan,Michael M. Rey,Justin F. Monroe,Katelyn M. Cannon,Lisa Blaskey,Sarah Woldoff,Saba Qasmieh,Michael J. Gandal,Gwen L. Schmidt,Deborah M. Zarnow,Susan E. Levy,J. Christopher Edgar +12 more
TL;DR: Given similar findings in language impaired and nonlanguage impaired ASD subjects, a right‐hemisphere M100 latency delay appears to be an electrophysiological endophenotype for autism.
Journal ArticleDOI
ECoG gamma activity during a language task: differentiating expressive and receptive speech areas.
Vernon L. Towle,Hyun Ah Yoon,Michael Castelle,J. Christopher Edgar,Nadia M. Biassou,David M. Frim,Jean-Paul Spire,Michael Kohrman +7 more
TL;DR: The data support the concept of distributed functionally specific language modules interacting to serve receptive and expressive speech, with frontal lobe 'corollary discharges' suppressing low-level receptive cortical language areas in the temporal lobe during speaking.