J
J. Cooper McDonald
Researcher at Harvard University
Publications - 12
Citations - 10798
J. Cooper McDonald is an academic researcher from Harvard University. The author has contributed to research in topics: PDMS stamp & Bacteriorhodopsin. The author has an hindex of 10, co-authored 12 publications receiving 10388 citations.
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Journal ArticleDOI
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
TL;DR: A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
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Poly(dimethylsiloxane) as a material for fabricating microfluidic devices.
TL;DR: This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS).
Journal ArticleDOI
Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping.
Janelle R. Anderson,Daniel T. Chiu,Rebecca J. Jackman,Oksana Cherniavskaya,J. Cooper McDonald,Hongkai Wu,Sue Whitesides,George M. Whitesides +7 more
TL;DR: This method can generate topologically complex microfluidic systems and can fabricate a membrane containing a channel that crosses over and under itself, but does not intersect itself and, therefore, can be fabricated in the form of any knot.
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Patterning cells and their environments using multiple laminar fluid flows in capillary networks.
Shuichi Takayama,J. Cooper McDonald,Emanuele Ostuni,Michael N. Liang,Paul J. A. Kenis,Rustem F. Ismagilov,George M. Whitesides +6 more
TL;DR: This method offers a way to simultaneously control the characteristics of the surface to which cells are attached, the type of cells that are in their vicinity, and the kind of media that cells or part of a cell are exposed to.
Journal ArticleDOI
An Integrated Fluorescence Detection System in Poly(dimethylsiloxane) for Microfluidic Applications
Michael L. Chabinyc,Daniel T. Chiu,J. Cooper McDonald,Abraham D. Stroock,James F. Christian,and Arieh M. Karger,George M. Whitesides +6 more
TL;DR: The device was used to detect the separation of a mixture of proteins and small molecules by capillary electrophoresis; the separation illustrated the suitability of this integrated fluorescence detection system for bioanalytical applications.