J
J D Lambeth
Researcher at Emory University
Publications - 64
Citations - 4804
J D Lambeth is an academic researcher from Emory University. The author has contributed to research in topics: Cytochrome & Adrenodoxin. The author has an hindex of 41, co-authored 64 publications receiving 4730 citations. Previous affiliations of J D Lambeth include Indiana University & Duke University.
Papers
More filters
Journal ArticleDOI
The neutrophil NADPH oxidase
TL;DR: The recent identification of homologs of one of the membrane components in nonphagocytic cells will expand understanding of the biological contexts in which this system may function.
Journal ArticleDOI
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.
TL;DR: It is demonstrated that incubation of cells with sphinganine or sphingosine blocks or reverses activation by these agonists and suggested that long-chain bases function as physiologic modulators of cellular regulatory pathways involving protein kinase C.
Journal ArticleDOI
Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein.
TL;DR: Olson et al. as discussed by the authors investigated the location of the GTP-binding protein by preincubating either cytosol or plasma membrane with GTP gamma S, followed by removal of all but tightly bound nucleotide and reconstituting activity with the complementing untreated subcellular fraction.
Journal ArticleDOI
Steroidogenic electron transport in adrenal cortex mitochondria.
TL;DR: Evidence supports the existence of a specific effector lipid binding site on cytochrome P.450scc to which this cholesterol binding site appears to be in direct communication with the hydrophobic phospholipid milieu in which this substrate is dissolved.
Journal ArticleDOI
Ionic effects on adrenal steroidogenic electron transport. The role of adrenodoxin as an electron shuttle.
TL;DR: Reduction-induced dissociation of adrenodoxin from Adrenodoxin reductase appears to be a required step in steroidogenic electron transport by this system, and a role for adrenodox in as a mobile electron shuttle is proposed.