J
J.-J. Grob
Researcher at Aix-Marseille University
Publications - 138
Citations - 2912
J.-J. Grob is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Nivolumab & Ipilimumab. The author has an hindex of 23, co-authored 126 publications receiving 2246 citations.
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Journal ArticleDOI
Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study.
Georgina V. Long,Keith T. Flaherty,Daniil Stroyakovskiy,Helen Gogas,Evgeny Levchenko,F. de Braud,James Larkin,Claus Garbe,Thomas Jouary,Axel Hauschild,Vanna Chiarion-Sileni,Céleste Lebbé,Mario Mandalà,Michael Millward,Ana Arance,Igor Bondarenko,J.B.A.G. Haanen,Johan Hansson,Jochen Utikal,Virginia Ferraresi,Peter Mohr,V. Probachai,Dirk Schadendorf,Paul Nathan,Caroline Robert,Antoni Ribas,Michael A. Davies,Stephen R. Lane,Jeffrey J. Legos,Bijoyesh Mookerjee,J.-J. Grob +30 more
TL;DR: It is demonstrated that durable (≥3 years) survival is achievable with dabrafenib plus trametinib in patients with BRAF V600-mutant metastatic melanoma and support long-term first-line use of the combination in this setting.
Journal ArticleDOI
Vismodegib in patients with advanced basal cell carcinoma: Primary analysis of STEVIE, an international, open-label trial.
Nicole Basset-Seguin,Axel Hauschild,Rainer Kunstfeld,J.-J. Grob,B. Dréno,Laurent Mortier,P.A. Ascierto,Lisa Licitra,C. Dutriaux,Luc Thomas,Nicolas Meyer,Bernard Guillot,Reinhard Dummer,Petr Arenberger,Kate Fife,A. Raimundo,Emi Dika,N. Dimier,A. Fittipaldo,I. Xynos,Johan Hansson +20 more
TL;DR: The primary analysis of STEVIE demonstrates that vismodegib is tolerable in typical patients in clinical practice; safety profile is consistent with that in previous reports.
Journal ArticleDOI
Guidelines for the diagnosis and treatment of cutaneous squamous cell carcinoma and precursor lesions.
J.J. Bonerandi,C. Beauvillain,L. Caquant,J.F. Chassagne,V. Chaussade,P. Clavère,C. Desouches,F. Garnier,J.L. Grolleau,M. Grossin,A. Jourdain,J.Y. Lemonnier,H. Maillard,N. Ortonne,E. Rio,E. Simon,J.F. Sei,J.-J. Grob,Ludovic Martin +18 more
TL;DR: Guidelines for the diagnosis and treatment of cutaneous squamous cell carcinoma and precursor lesions J.J. Martin,* for the French Dermatology Recommendations Association (aRED)
Journal ArticleDOI
Comparative study of the impact of chronic urticaria, psoriasis and atopic dermatitis on the quality of life
TL;DR: A knowledge of their impact from the patient's point of view is required for a better management of chronic skin disorders.
Journal ArticleDOI
Adjuvant prophylactic regional radiotherapy versus observation in stage I Merkel cell carcinoma: a multicentric prospective randomized study
Thomas Jouary,C. Leyral,Brigitte Dréno,Adélaïde Doussau,Bruno Sassolas,Marie Beylot-Barry,C. Renaud-Vilmer,Bernard Guillot,Philippe Bernard,C. Lok,Christophe Bedane,Frédéric Cambazard,Laurent Misery,Eric Estève,Sophie Dalac,Laurent Machet,Florent Grange,P. Young,Florence Granel-Brocard,François Truchetet,B. Vergier,Michèle Delaunay,J.-J. Grob +22 more
TL;DR: The adjuvant regional irradiation significantly decreased the PRR in MCC, but benefit in survival could not be demonstrated and the treatment was well tolerated.