Sophie Dalac

TL;DR: A germline missense substitution in MITF (Mi-E318K) is identified that occurred at a significantly higher frequency in genetically enriched patients affected with melanoma, RCC or both cancers, when compared with controls and provides insights into the link between SUMOylation, transcription and cancer.

TL;DR: The major clinical, histopathologic, and phenotypic aspects of the disease and diagnostic criteria and data suggesting a plasmacytoid dendritic cell origin for the tumor cells are provided.

TL;DR: It is proposed that oncogenic transformation of NCAM-expressing plasmacytoid monocyte-like cells may lead to “agranular CD4+ CD56+ hematodermic neoplasm” and a rare population of cells that is identified in the peripheral blood of healthy volunteers treated with Flt3 ligand is presented.

TL;DR: Primary cutaneous diffuse large B-cell lymphoma, leg type is a distinct entity with a poor prognosis, particularly in patients with multiple tumors on the legs, but the prognosis could be improved with combinations of anthracycline-containing chemotherapies and rituximab.

TL;DR: Seven cases of particular cutaneous tumors selected from the register of the French Study Group on Cutaneous Lymphomas seem to represent a distinct entity likely developed from hematological precursor cells, although CD4 and CD56 are not specific for T or natural killer lineages.