J
J. M. de la Fuente
Researcher at University of Zaragoza
Publications - 9
Citations - 401
J. M. de la Fuente is an academic researcher from University of Zaragoza. The author has contributed to research in topics: Nanocarriers & Fibroin. The author has an hindex of 8, co-authored 9 publications receiving 350 citations.
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Notice of Violation of IEEE Publication Principles Nuclear Localization of HIV-1 Tat Functionalized Gold Nanoparticles
TL;DR: Water soluble, biocompatible gold nanoparticles of differing size functionalized with the HIV-1 tat PTD are developed with the aim of producing nuclear targeting agents and results demonstrate successful nanoparticle transfer across the plasma membrane.
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Designing novel nano-immunoassays: antibody orientation versus sensitivity
Sara Puertas,María Moros,Rodrigo Fernández-Pacheco,M. R. Ibarra,Valeria Grazú,J. M. de la Fuente +5 more
TL;DR: The importance of nanoparticle functionalization for the improvement of sensitivity for a lateral-flow immunoassay is reported and it is found that immobilization of IgG anti-hCG through its polysaccharide moieties on MNPs allows more successful recognition of the hCG hormone.
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Functionalized Fe₃O₄@Au superparamagnetic nanoparticles: in vitro bioactivity.
J. Salado,Maite Insausti,Luis Lezama,I. Gil de Muro,María Moros,Beatriz Pelaz,Valeria Grazú,J. M. de la Fuente,Teófilo Rojo +8 more
TL;DR: It was demonstrated that nanoparticles clearly interacted with the cells, showing a higher level of accumulation in the cells for glucose conjugated nanoparticles, which enhances the superparamagnetic behaviour observed above 10-15 K in this kind of nanoparticle.
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Intestinal anti-inflammatory effects of RGD-functionalized silk fibroin nanoparticles in trinitrobenzenesulfonic acid-induced experimental colitis in rats.
Alba Rodríguez-Nogales,Francesca Algieri,Laura De Matteis,A. Abel Lozano-Pérez,José Garrido-Mesa,Teresa Vezza,J. M. de la Fuente,José Luis Cenis,Julio Gálvez,María Elena Rodríguez-Cabezas +9 more
TL;DR: In this article, the interaction of the silk fibroin nanoparticles (SFNs) with the injured intestinal tissue by functionalizing them with the peptide motif RGD (arginine-glycine-aspartic acid) and to evaluate the intestinal anti-inflammatory properties of these RGD-functionalized silk fiber-SFNs in the trinitrobenzenesulfonic acid (TNBS) model of rat colitis.
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New active formulations against M. tuberculosis: Bedaquiline encapsulation in lipid nanoparticles and chitosan nanocapsules
L. De Matteis,Dorothée Jary,Ainhoa Lucía,Ainhoa Lucía,Sonia García-Embid,Inés Serrano-Sevilla,D. Pérez,José A. Aínsa,José A. Aínsa,Fabrice Navarro,J. M. de la Fuente +10 more
TL;DR: The promising behaviour of drug-loaded nanocarriers will hopefully lead to a reduction of the administered doses of a quite dangerous drug as bedaquiline, tuning its biodistribution and so decreasing its adverse effects, finally allowing its use in a higher number of patients.