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J. Michael Conlon

Researcher at Ulster University

Publications -  363
Citations -  12143

J. Michael Conlon is an academic researcher from Ulster University. The author has contributed to research in topics: Peptide & Antimicrobial peptides. The author has an hindex of 51, co-authored 356 publications receiving 11461 citations. Previous affiliations of J. Michael Conlon include University of New South Wales & University of Rouen.

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Journal ArticleDOI

Antimicrobial peptides from ranid frogs: taxonomic and phylogenetic markers and a potential source of new therapeutic agents.

J. Michael Conlon, +3 more
- 14 Jan 2004 - 
TL;DR: The broad-spectrum antibacterial and antifungal activities of certain peptides, for example esculentin-1, ranalexin-1 and ranatuerin, together with their relatively low hemolytic activity, make them candidates for development into therapeutically useful anti-infective agents.
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Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord

Yolaine Coulouarn, +8 more
- 22 Dec 1998 - 
TL;DR: The present study demonstrates that UII, which has long been regarded as a peptide exclusively produced by the urophysis of teleost fish, is actually present in the brain of amphibians and mammals.
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Activity of antimicrobial skin peptides from ranid frogs against Batrachochytrium dendrobatidis, the chytrid fungus associated with global amphibian declines

Louise A. Rollins-Smith, +6 more
- 01 Jun 2002 - 
TL;DR: It is shown that 10 peptides representing eight families of peptides derived from North American ranid frogs can effectively inhibit growth of this chytrid fungus, suggesting that the ranidfrogs have, within their repertoire of antimicrobial substances, a number of skin peptides that should be a deterrent to chyTrid infection.
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Antimicrobial peptide defenses against chytridiomycosis, an emerging infectious disease of amphibian populations

Louise A. Rollins-Smith, +1 more
- 01 Jan 2005 - 
TL;DR: Data is presented to show that antimicrobial peptides, produced in granular glands of the skin and released in high concentrations into skin secretions, are highly effective in inhibiting growth of B. dendrobatidis in vitro and may provide limited protection for some species.
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Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.

Jadvinder Goraya, +6 more
- 01 Feb 2000 - 
TL;DR: Despite the close phylogenetic relationship between the various species of Ranid frogs, the distribution and amino-acid sequences of the antimicrobial peptides produced by each species are highly variable and species-specific, suggesting that they may be valuable in taxonomic classification and molecular phylogenetic analysis.